Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494467 | 0.84 | BAZ2B (0.44) | BAZ2BSMN1; SMN2LCKMAPK14POLB | |
| SCHEMBL6866811 | 0.78 | NLRP3 (0.57) | BAZ2BSMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL22013712 | 0.75 | NLRP3 (0.54) | BAZ2BSMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL20194506 | 0.75 | NLRP3 (0.53) | SMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL1673429 | 0.72 | BAZ2B (0.69) | BAZ2BSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL20713466 | 0.69 | NLRP3 (0.54) | SMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL18737818 | 0.69 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNARAB9AHTTNPSR1 | |
| SCHEMBL2245582 | 0.69 | BAZ2B (0.64) | BAZ2BSMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL9139676 | 0.69 | NPC1 (0.71) | SMN1; SMN2POLBNPC1RAB9ATP53 | |
| SCHEMBL14211464 | 0.68 | POLB (0.54) | SMN1; SMN2POLBNPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | claimed |
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |