Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494480 | 0.88 | MEN1 (0.42) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29494344 | 0.84 | BAZ2B (0.49) | BAZ2BPOLBMAPK14LCKSMN1; SMN2 | |
| SCHEMBL29494419 | 0.82 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1673429 | 0.68 | BAZ2B (0.69) | BAZ2BPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29494530 | 0.68 | NPC1 (0.51) | POLBMAPK14LCKMEN1KMT2A | |
| SCHEMBL6866811 | 0.67 | NLRP3 (0.57) | BAZ2BSMN1; SMN2ALDH1A1NLRP3 | |
| SCHEMBL14211464 | 0.67 | POLB (0.54) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL25832722 | 0.65 | NLRP3 (0.51) | NLRP3 | |
| SCHEMBL18737818 | 0.65 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL18617653 | 0.65 | MMP13 (0.56) | POLBMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |