Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552228 | 0.89 | ADK (0.41) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL1065626 | 0.87 | LMNA (0.44) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL12937913 | 0.83 | LMNA (0.62) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL6297249 | 0.83 | LMNA (0.62) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL19657184 | 0.83 | LMNA (0.62) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL2583859 | 0.83 | LMNA (0.62) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL770113 | 0.83 | LMNA (0.62) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL12230437 | 0.83 | LMNA (0.62) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL770112 | 0.83 | LMNA (0.62) | ADKLMNAMTORTHRBMDM2 | |
| SCHEMBL903023 | 0.83 | P2RY2 (0.55) | P2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983077-A1 | DELIVERY OF OLIGONUCLEOTIDES TO THE STRIATUM | Alnylam Pharmaceuticals, Inc. (US) | 2022-04-20 | — | — | EP | disclosed |