SCHEMBL770112

SCHEMBL770112

Nc1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1I

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.62
MTOR P42345 2/20 0.62
ALDH1A1 P00352 2/20 0.62
THRB P10828 1/20 0.62
MDM2 Q00987 1/20 0.62
NCOA1 Q15788 1/20 0.62
NCOA3 Q9Y6Q9 1/20 0.62
GMNN O75496 1/20 0.62
TP53 P04637 1/20 0.62
NFKB1 P19838 1/20 0.62
DNMT1 P26358 1/20 0.62
THPO P40225 1/20 0.62
HTT P42858 1/20 0.62
RAB9A P51151 1/20 0.62
BLM P54132 1/20 0.62
HBB P68871 1/20 0.62
PMP22 Q01453 1/20 0.62
PYGM P11217 1/20 0.57
MAPT P10636 1/20 0.52
CDA P32320 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2583859 1.00 LMNA (0.62) LMNAMTORALDH1A1THRBMDM2
SCHEMBL12937913 1.00 LMNA (0.62) LMNAMTORALDH1A1THRBMDM2
SCHEMBL19657184 1.00 LMNA (0.62) LMNAMTORALDH1A1THRBMDM2
SCHEMBL770113 1.00 LMNA (0.62) LMNAMTORALDH1A1THRBMDM2
SCHEMBL12230437 1.00 LMNA (0.62) LMNAMTORALDH1A1THRBMDM2
SCHEMBL6297249 1.00 LMNA (0.62) LMNAMTORALDH1A1THRBMDM2
Phosphoric Acid SCHEMBL20240168 0.95 LMNA (0.57) LMNAMTORALDH1A1THRBMDM2
Phosphoric Acid SCHEMBL5501341 0.95 LMNA (0.57) LMNAMTORALDH1A1THRBMDM2
SCHEMBL24826957 0.89 LMNA (0.49) LMNAMTORALDH1A1THRBMDM2
Fiacitabine SCHEMBL138934 0.89 PDE2A (0.50) LMNAMTORALDH1A1THRBMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2373 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711452-A2 KLOTHO MRNA ADvantage Therapeutics, Inc. (US) 2026-03-18 EP claimed
EP-4676525-A2 CORONAVIRUS VACCINES DIOSynVax Ltd (GB) 2026-01-14 EP claimed
US-20250367301-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT INTEROLIGO CORPORATION (KR) 2025-12-04 US claimed
US-20250340868-A1 POLYNUCLEOTIDES ENCODING LINKED ANTIGENS AND USES THEREOF STEMCELL TECHNOLOGIES CANADA INC (CA) 2025-11-06 US claimed
US-12448624-B2 Modified nucleic acid having improved treatment efficacy, and anticancer pharmaceutical composition containing same INTEROLIGO CORPORATION (KR) 2025-10-21 US claimed
US-12343420-B2 Stabilized polyribonucleotide coding for an elastic fibrous protein EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) 2025-07-01 US claimed
EP-4561602-A1 POLYNUCLEOTIDES ENCODING LINKED ANTIGENS AND USES THEREOF Stemcell Technologies Canada Inc. (CA) 2025-06-04 EP claimed
US-20250161488-A1 THERAPEUTIC mRNA THE UNIVERSITY OF MELBOURNE (AU) 2025-05-22 US claimed
US-20250152737-A1 LIPID NANOPARTICLES COMPRISING VENEZUELAN EQUINE ENCEPHALITIS (VEE) REPLICON AND USES THEREOF STRAND THERAPEUTICS INC. (US) 2025-05-15 US claimed
EP-4553084-A2 USE OF IFN-LAMBDA MRNA FOR TREATING VIRAL INFECTIONS Ethris GmbH (DE) 2025-05-14 EP claimed
WO-2004046324-A2 ALLELE-TARGETED RNA INTERFERENCE UNIVERSITY OF MASSACHUSETTS (US) 2004-06-03 WO claimed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 US claimed
US-6635427-B2 Kit for use in the amplification and quantification of preferential sequences UNIVERSITY OF UTAH RESEARCH FOUNDATION 2003-10-21 US claimed
EP-1307592-A2 SINGLE-LABELED OLIGONUCLEOTIDE PROBES University of Utah Research Foundation (US) 2003-05-07 EP claimed
US-20030022177-A1 Single-labeled oligonucleotide probes for homogeneous nucleic acid sequence analysis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-30 US claimed
WO-2002014555-A2 SINGLE-LABELED OLIGONUCLEOTIDE PROBES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2002-02-21 WO claimed
WO-2000018780-A1 NUCLEOSIDE MODIFICATIONS BY PALLADIUM CATALYZED METHODS NEXSTAR PHARMACEUTICALS, INC. (US) 2000-04-06 WO claimed
US-6020483-A Nucleoside modifications by palladium catalyzed methods NEXSTAR PHARMACEUTICALS, INC. (US) 2000-02-01 US claimed
EP-0828750-A1 PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE NeXstar Pharmaceuticals, Inc. (US) 1998-03-18 EP claimed
WO-1996038460-A1 PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE NEXSTAR PHARMACEUTICALS, INC. (US) 1996-12-05 WO claimed