Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL27718494 | 1.00 | ADRB3 (0.37) | ADRB3PPARGEPHX2HTR6ADRB2 | |
| SCHEMBL13240103 | 0.97 | ADRB3 (0.39) | ADRB3PPARGHTR6ADRB2ADRB1 | |
| Trifluoroacetic Acid SCHEMBL2946086 | 0.92 | ADRB3 (0.38) | ADRB3PPARGEPHX2HTR6EGFR | |
| Trifluoroacetic Acid SCHEMBL2948619 | 0.92 | GAA (0.40) | ADRB3PPARGEPHX2HTR6ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2948283 | 0.91 | ADRB3 (0.40) | ADRB3PPARGHTR6ADRB2ADRB1 | |
| Trifluoroacetic Acid SCHEMBL2944135 | 0.91 | ADRB3 (0.40) | ADRB3PPARGHTR6ADRB2ADRB1 | |
| Trifluoroacetic Acid SCHEMBL2945085 | 0.90 | ADRB3 (0.41) | ADRB3PPARGEPHX2HTR6ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2951304 | 0.90 | ADRB3 (0.42) | ADRB3PPARGEPHX2HTR6ADRB2 | |
| SCHEMBL27718492 | 0.90 | OPRM1 (0.35) | ADRB3PPARGEPHX2HTR6EGFR | |
| Trifluoroacetic Acid SCHEMBL2941086 | 0.89 | ADRB3 (0.39) | ADRB3HTR6ADRB2ADRB1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754756-B2 | Indol-containing beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-13 | — | — | US | disclosed |
| US-20070105906-A1 | Indol-containing beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105906-A1 | Indol-containing beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | ADRB1, ADRB3, ADRB2 | ADRB3 2/4885PPARG 662/4885EPHX2 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.