Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722474 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL14397720 | 0.86 | KMT2A (0.54) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL4659282 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL7300773 | 0.81 | TSHR (0.57) | ALDH1A1KDM4EMAPTTSHRNPC1 | |
| SCHEMBL4791655 | 0.79 | HTR2A (0.48) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL22936210 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL29739524 | 0.78 | POLB (0.54) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL29177207 | 0.78 | POLB (0.54) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL29277214 | 0.77 | TSHR (0.67) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL4768514 | 0.77 | HTR2A (0.49) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114423753-A | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2022-04-29 | — | — | CN | disclosed |