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Tyrosine

Tyrosine

SCHEMBL294953

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SSTR1SSTR2SSTR3SSTR5

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 2/20 0.38
▸ NPY1R P25929 3/20 0.34
▸ SLC7A5 Q01650 1/20 0.34
▸ ITGA4 P13612 4/20 0.33
▸ BACE1 P56817 1/20 0.32
▸ KDM1A O60341 1/20 0.32
▸ NTSR2 O95665 3/20 0.32
▸ NTSR1 P30989 3/20 0.32
▸ SORT1 Q99523 2/20 0.32
▸ KISS1R Q969F8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL5151728 0.95 REN (0.36) RENNPY1RSLC7A5ITGA4NTSR2
Tyrosine SCHEMBL20855327 0.93 REN (0.35) RENNPY1RSLC7A5ITGA4NTSR2
Tyrosine SCHEMBL28490008 0.92 REN (0.39) RENNPY1RKDM1AKISS1R
Tyrosine SCHEMBL28889532 0.91 SLC7A5 (0.38) RENSLC7A5ITGA4KDM1AKISS1R
Tyrosine SCHEMBL10380759 0.91 SLC7A5 (0.41) RENSLC7A5ITGA4
Tyrosine SCHEMBL6253686 0.91 REN (0.38) RENNPY1RKDM1AKISS1R
Tyrosine SCHEMBL10379802 0.88 SLC7A5 (0.38) RENSLC7A5ITGA4
Tyrosine SCHEMBL18339169 0.87 SLC7A5 (0.44) RENNPY1RSLC7A5ITGA4
Tyrosine SCHEMBL28702925 0.86 NTSR2 (0.36) RENNPY1RSLC7A5ITGA4KDM1A
Tyrosine SCHEMBL27454138 0.86 REN (0.35) RENSLC7A5ITGA4NTSR2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463378-B1 Alpha isomaltosylglucosaccharide synthase, process for producing the same and use thereof HAYASHIBARA CO (JP) 2015-12-23 — — EP disclosed
EP-2463378-A1 Alpha isomaltosylglucosaccharide synthase, process for producing the same and use thereof KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 2012-06-13 — — EP disclosed
EP-1229112-B1 ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF HAYASHIBARA BIOCHEM LAB (JP) 2012-03-14 — — EP disclosed
EP-1284286-B1 ALPHA-ISOMALTOSYLTRANSFERASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF HAYASHIBARA BIOCHEM LAB (JP) 2011-11-09 — — EP disclosed
EP-1445325-B1 PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF HAYASHIBARA BIOCHEM LAB (JP) 2010-05-26 — — EP disclosed
EP-1445325-A1 PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2004-08-11 — — EP disclosed
EP-1284286-A1 ALPHA-ISOMALTOSYLTRANSFERASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2003-02-19 — — EP disclosed
EP-1229112-A1 ALPHA-ISOMALTOSYLGLUCOSACCHARIDE SYNTHASE, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2002-08-07 — — EP disclosed