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Tyrosine

Tyrosine

SCHEMBL5151728

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 2/20 0.36
▸ NPY1R P25929 4/20 0.35
▸ SLC7A5 Q01650 1/20 0.32
▸ NTSR2 O95665 4/20 0.32
▸ NTSR1 P30989 4/20 0.32
▸ ITGA4 P13612 3/20 0.32
▸ SORT1 Q99523 2/20 0.31
▸ NPY2R P49146 1/20 0.31
▸ NPY4R P50391 1/20 0.31
▸ NPY5R Q15761 1/20 0.31
▸ KISS1R Q969F8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL20855327 0.98 REN (0.35) RENNPY1RSLC7A5NTSR2NTSR1
Tyrosine SCHEMBL294953 0.95 REN (0.38) RENNPY1RSLC7A5NTSR2NTSR1
Tyrosine SCHEMBL28490008 0.90 REN (0.39) RENNPY1RKISS1R
Tyrosine SCHEMBL10380759 0.89 SLC7A5 (0.41) RENSLC7A5ITGA4
Tyrosine SCHEMBL6253686 0.89 REN (0.38) RENNPY1RKISS1R
Glutamine SCHEMBL17713530 0.89 ALOX15 (0.32) RENSLC7A5
Tyrosine SCHEMBL9617523 0.88 REN (0.39) RENSLC7A5ITGA4
Tyrosine SCHEMBL28889532 0.86 SLC7A5 (0.38) RENSLC7A5ITGA4KISS1R
Tyrosine SCHEMBL10379802 0.86 SLC7A5 (0.38) RENSLC7A5ITGA4
Leucine SCHEMBL5151721 0.86 REN (0.34) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070032410-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PSYCHIATRIC DISORDERS ATOSSA HEALTHCARE, INC. 2007-02-08 — — US disclosed