Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671041 | 1.00 | REV1 (0.35) | REV1BACE1PLAUNCF1 | |
| SCHEMBL22969282 | 0.84 | REN (0.37) | — | |
| SCHEMBL29495862 | 0.84 | PLAU (0.37) | REV1BACE1PLAUNCF1 | |
| SCHEMBL24671045 | 0.84 | PLAU (0.37) | REV1BACE1PLAUNCF1 | |
| SCHEMBL29496037 | 0.75 | PLAU (0.37) | BACE1PLAUNCF1 | |
| SCHEMBL24671592 | 0.75 | PLAU (0.37) | BACE1PLAUNCF1 | |
| SCHEMBL24671040 | 0.67 | CCR1 (0.41) | REV1BACE1PLAUNCF1 | |
| SCHEMBL24671049 | 0.67 | FGFR1 (0.35) | BACE1 | |
| SCHEMBL29495873 | 0.67 | FGFR1 (0.35) | BACE1 | |
| SCHEMBL29495772 | 0.64 | USP7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | claimed |
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |