Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736778 | 0.72 | DAO (0.61) | DAOKDM4EKMT2ASMN1; SMN2DDB1 | |
| SCHEMBL13757029 | 0.72 | DAO (0.53) | DAOKDM4EKMT2AHPGDLMNA | |
| SCHEMBL22969446 | 0.71 | GABRP (0.38) | KMT2AMAPK1GABRPGABRDGABRA1 | |
| SCHEMBL29495952 | 0.71 | GABRP (0.38) | KMT2AMAPK1GABRPGABRDGABRA1 | |
| SCHEMBL3138039 | 0.71 | DAO (0.46) | DAOKDM4EKMT2AHPGDLMNA | |
| SCHEMBL29496012 | 0.71 | NPC1 (0.51) | KDM4EKMT2AALDH1A1ATMMEN1 | |
| SCHEMBL10757723 | 0.70 | DAO (0.59) | DAOKDM4EKMT2AHPGDLMNA | |
| SCHEMBL30349848 | 0.70 | DAO (0.62) | DAOKDM4EKMT2AHPGDMAPT | |
| SCHEMBL8538250 | 0.70 | DAO (0.62) | DAOKDM4EKMT2AHPGDMAPT | |
| SCHEMBL17025698 | 0.70 | DAO (0.54) | DAOKDM4EKMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269730-A | 5-heteroaryl-pyridin-2-amine compounds as neuropeptide FF receptor antagonists | 多曼治疗学公司 | 2022-04-01 | — | — | CN | disclosed |