Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 2/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lomerizine SCHEMBL79390 | 1.00 | LMNA (1.00) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL29439945 | 0.99 | LMNA (0.98) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL404179 | 0.99 | LMNA (0.98) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL1153647 | 0.99 | LMNA (0.98) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL1650277 | 0.98 | LMNA (0.95) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| SCHEMBL1152274 | 0.95 | LMNA (0.91) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Hydrochloric Acid SCHEMBL7324923 | 0.94 | LMNA (0.89) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL10731133 | 0.91 | LMNA (0.82) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL10731150 | 0.91 | LMNA (0.82) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| SCHEMBL6138969 | 0.90 | LMNA (0.81) | LMNACHRM2OPRK1ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498297-B1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM | STALICLA S A (CH) | 2023-06-21 | — | — | EP | claimed |
| CN-115466561-B | Casein modified water-based breathable coating and application thereof | 上海欧畅新材料科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-116507327-A | Chewable formulations | 礼蓝动物保健有限公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-3498297-B1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM | STALICLA S A (CH) | 2023-06-21 | — | — | EP | disclosed |
| CN-115466561-A | Casein modified water-based breathable coating and application thereof | 上海欧畅新材料科技有限公司 | 2022-12-13 | — | — | CN | disclosed |
| US-11439627-B2 | Pharmaceutical composition for the treatment of autism | Stalicla S.A. (CH) | 2022-09-13 | — | — | US | disclosed |
| EP-3984555-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM | Stalicla S.A. (CH) | 2022-04-20 | — | — | EP | disclosed |