Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 2/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | HTR2C | P28335 | 1/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 1/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lomerizine SCHEMBL29496366 | 1.00 | LMNA (1.00) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL29439945 | 0.99 | LMNA (0.98) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL404179 | 0.99 | LMNA (0.98) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL1153647 | 0.99 | LMNA (0.98) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL1650277 | 0.98 | LMNA (0.95) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| SCHEMBL1152274 | 0.95 | LMNA (0.91) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Hydrochloric Acid SCHEMBL7324923 | 0.94 | LMNA (0.89) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL10731133 | 0.91 | LMNA (0.82) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| Lomerizine SCHEMBL10731150 | 0.91 | LMNA (0.82) | LMNACHRM2OPRK1ADORA3CHRM1 | |
| SCHEMBL6138969 | 0.90 | LMNA (0.81) | LMNACHRM2OPRK1ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4085 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| EP-4631504-A1 | COMPOSITION FOR PREVENTION OR TREATMENT OF FABRY'S DISEASE | Korea Advanced Institute of Science and Technology (KR) | 2025-10-15 | — | — | EP | claimed |
| WO-2024211216-A1 | CILNIDIPINE AND A P-GLYCOPROTEIN INHIBITOR FOR TREATING PAIN | AISA PHARMA, INC. (US) | 2024-10-10 | — | — | WO | claimed |
| US-20240299348-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. | 2024-09-12 | — | — | US | claimed |
| WO-2024158908-A1 | METHODS OF TREATING BACTERIAL INFECTIONS | EMORY UNIVERSITY (US) | 2024-08-02 | — | — | WO | claimed |
| WO-2024123129-A1 | COMPOSITION FOR PREVENTION OR TREATMENT OF FABRY'S DISEASE | 한국과학기술원 | 2024-06-13 | — | — | WO | claimed |
| CN-117982504-A | Application of lomerizine in preparation of medicines for treating oral cancer | 天津济坤医药科技有限公司 | 2024-05-07 | — | — | CN | claimed |
| WO-2023183932-A2 | MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | claimed |
| US-11390868-B2 | Treatment of filaggrin (FLG) related diseases by modulation of FLG expression and activity | CURNA, INC. (US) | 2022-07-19 | — | — | US | claimed |
| WO-2022150461-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2022-07-14 | — | — | WO | claimed |
| EP-0861081-B1 | USE OF EPINASTINE IN THE TREATMENT OF PAIN | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-02-13 | — | — | EP | claimed |
| WO-2002009761-A2 | EPOXY-STEROIDAL ALDOSTERONE ANTAGONIST AND CALCIUM CHANNEL BLOCKER COMBINATION THERAPY FOR TREATMENT OF CONGESTIVE HEART FAILURE | PHARMACIA CORPORATION (US) | 2002-02-07 | — | — | WO | claimed |
| CN-1315945-A | Nitrate salts of antihypertensive drugs | NICOX SA (FR) | 2001-10-03 | — | — | CN | claimed |
| CN-1295475-A | Medicine for improving optic disc circulation | ACKERSO NOBEL B V (NL) | 2001-05-16 | — | — | CN | claimed |
| EP-1087953-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 2001-04-04 | — | — | EP | claimed |
| EP-1051973-A1 | OPTIC PAPILLARY CIRCULATION IMPROVING AGENTS | Akzo Nobel N.V. (NL) | 2000-11-15 | — | — | EP | claimed |
| WO-1999067231-A1 | NITRATE SALTS OF ANTIHYPERTENSIVE MEDICINES | NICOX S.A. (FR) | 1999-12-29 | — | — | WO | claimed |
| US-5942503-A | Use of Epinastine for the treatment of pain | BOEHRINGER INDELHEIM KG (DE) | 1999-08-24 | — | — | US | claimed |
| US-4663325-A | 1-(2,3,4-tri-methoxybenzyl)-4[bis(4-fluorophenyl)methyl] piperazines are useful for treating cerebrovascular disease | KANEBO LTD. (JP) | 1987-05-05 | — | — | US | claimed |
| EP-0159566-A1 | Novel piperazine derivatives, processes for production thereof, and pharmaceutical compositions comprising said compounds as active ingredient | KANEBO, LTD. (JP) | 1985-10-30 | — | — | EP | claimed |