SCHEMBL30193454

SCHEMBL30193454

C[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CCCNC(N)=O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 3/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ DPP7 Q9UHL4 1/20 0.42
▸ NRP1 O14786 2/20 0.42
▸ C3AR1 Q16581 1/20 0.37
▸ MASP2 O00187 3/20 0.36
▸ MAPK8 P45983 1/20 0.36
▸ MAPK9 P45984 1/20 0.36
▸ MAPK10 P53779 1/20 0.36
▸ CPB2 Q96IY4 1/20 0.36
▸ CALCRL Q16602 1/20 0.36
▸ F2 P00734 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496505 0.92 PRCP (0.42) PRCPMEN1KMT2ADPP7NRP1
SCHEMBL30193521 0.90 MEN1 (0.45) PRCPMEN1KMT2ADPP7C3AR1
SCHEMBL31572023 0.90 MEN1 (0.48) PRCPMEN1KMT2ADPP7C3AR1
SCHEMBL29886918 0.90 PRCP (0.42) PRCPMEN1KMT2ADPP7C3AR1
SCHEMBL29947814 0.87 PRCP (0.44) PRCPMEN1KMT2ADPP7CALCRL
SCHEMBL29947667 0.87 EED (0.41) PRCPMEN1KMT2ADPP7MAPK8
SCHEMBL29535027 0.86 CPB2 (0.46) MEN1KMT2ADPP7CPB2
SCHEMBL30193219 0.85 MEN1 (0.42) PRCPMEN1KMT2ADPP7C3AR1
SCHEMBL30193311 0.85 MEN1 (0.42) PRCPMEN1KMT2ADPP7C3AR1
SCHEMBL30416888 0.85 MAPK8 (0.42) PRCPMEN1KMT2ADPP7NRP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250262312-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2025-08-21 — — US disclosed
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-11-07 — — US disclosed
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds SEAGEN INC. (US) 2024-07-16 — — US disclosed
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC (US) 2024-06-27 — — US disclosed
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS SEAGEN INC. 2023-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207427-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ PRCP 20/4885MEN1 1450/4885KMT2A 3707/4885
US-20240366779-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ PRCP 20/4885MEN1 1450/4885KMT2A 3707/4885
US-20250262312-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ PRCP 20/4885MEN1 1450/4885KMT2A 3707/4885
US-12036286-B2 Selective drug release from internalized conjugates of biologically active compounds CTSB, CTSE, CTSZ PRCP 20/4885MEN1 1450/4885KMT2A 3707/4885
US-20230091653-A1 SELECTIVE DRUG RELEASE FROM INTERNALIZED CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS CTSB, CTSE, CTSZ PRCP 20/4885MEN1 1450/4885KMT2A 3707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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