SCHEMBL29498244

SCHEMBL29498244

N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 5/20 0.40
▸ DPP8 Q6V1X1 3/20 0.40
▸ DPP9 Q86TI2 3/20 0.40
▸ OPRM1 P35372 1/20 0.39
▸ F2 P00734 3/20 0.38
▸ DPP7 Q9UHL4 2/20 0.37
▸ FAP Q12884 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29498239 0.96 DPP4 (0.38) DPP4DPP8DPP9OPRM1F2
SCHEMBL10864928 0.87 OPRM1 (0.43) DPP4DPP8DPP9OPRM1
SCHEMBL5734357 0.86 DPP4 (0.44) DPP4DPP8DPP9F2DPP7
SCHEMBL4595209 0.86 DPP4 (0.44) DPP4DPP8DPP9F2DPP7
SCHEMBL4595206 0.86 DPP4 (0.44) DPP4DPP8DPP9F2DPP7
Bromide SCHEMBL10345828 0.86 OPRM1 (0.42) DPP4DPP8DPP9OPRM1
SCHEMBL7271617 0.85 NPSR1 (0.46) DPP4DPP8DPP9OPRM1
SCHEMBL29630457 0.85 MC4R (0.42) F2
SCHEMBL10420021 0.85 OPRM1 (0.41) DPP4DPP8DPP9OPRM1F2
SCHEMBL29776002 0.85 OPRM1 (0.51) OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024132726-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 — — WO claimed
US-11833220-B2 Artificial multi-antigen fusion protein and preparation and use thereof OXFORD VACMEDIX UK LTD. (GB) 2023-12-05 — — US disclosed
EP-3971215-A2 ARTIFICIAL MULTI-ANTIGEN FUSION PROTEIN AND PREPARATION AND USE THEREOF Oxford Vacmedix UK Ltd. (GB) 2022-03-23 — — EP disclosed
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