SCHEMBL29498239

SCHEMBL29498239

N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 3/20 0.38
▸ DPP8 Q6V1X1 1/20 0.38
▸ DPP9 Q86TI2 1/20 0.38
▸ OPRM1 P35372 1/20 0.37
▸ F2 P00734 2/20 0.36
▸ CTSL P07711 1/20 0.36
▸ CTSS P25774 1/20 0.36
▸ CTSK P43235 1/20 0.36
▸ CHRM2 P08172 1/20 0.35
▸ CHRM4 P08173 1/20 0.35
▸ CHRM5 P08912 1/20 0.35
▸ CHRM1 P11229 1/20 0.35
▸ CHRM3 P20309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29498244 0.96 DPP4 (0.40) DPP4DPP8DPP9OPRM1F2
SCHEMBL31201041 0.84 CTSL (0.41) OPRM1F2CTSLCTSSCTSK
SCHEMBL29568748 0.84 APLNR (0.41) OPRM1F2CTSLCTSSCTSK
SCHEMBL10864928 0.83 OPRM1 (0.43) DPP4DPP8DPP9OPRM1
SCHEMBL4595209 0.83 DPP4 (0.44) DPP4DPP8DPP9F2
SCHEMBL5734357 0.83 DPP4 (0.44) DPP4DPP8DPP9F2
SCHEMBL4595206 0.83 DPP4 (0.44) DPP4DPP8DPP9F2
Bromide SCHEMBL10345828 0.82 OPRM1 (0.42) DPP4DPP8DPP9OPRM1
SCHEMBL29565378 0.82 CTSL (0.40) OPRM1F2CTSLCTSSCTSK
SCHEMBL7271617 0.82 NPSR1 (0.46) DPP4DPP8DPP9OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12472245-B2 Compositions and methods CHAIN BIOTECHNOLOGY LIMITED (GB) 2025-11-18 — — US disclosed
US-20250213673-A1 COMPOSITIONS AND METHODS CHAIN BIOTECHNOLOGY LIMITED (GB) 2025-07-03 — — US disclosed
US-20240058433-A1 COMPOSITIONS AND METHODS CHAIN BIOTECHNOLOGY LTD (GB) 2024-02-22 — — US disclosed
US-11833220-B2 Artificial multi-antigen fusion protein and preparation and use thereof OXFORD VACMEDIX UK LTD. (GB) 2023-12-05 — — US disclosed
EP-4262861-A1 COMPOSITIONS AND METHODS Chain Biotechnology Limited (GB) 2023-10-25 — — EP disclosed
WO-2022129881-A1 COMPOSITIONS AND METHODS CHAIN BIOTECHNOLOGY LIMITED (GB) 2022-06-23 — — WO disclosed
EP-3971215-A2 ARTIFICIAL MULTI-ANTIGEN FUSION PROTEIN AND PREPARATION AND USE THEREOF Oxford Vacmedix UK Ltd. (GB) 2022-03-23 — — EP disclosed
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