Catestatin

Catestatin

SCHEMBL29498741

CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ NMUR2 Q9GZQ4 3/20 0.58
▸ NMUR1 Q9HB89 3/20 0.58
▸ APLNR P35414 1/20 0.57
▸ NPY2R P49146 5/20 0.57
▸ NPY4R P50391 5/20 0.57
▸ NPY5R Q15761 5/20 0.57
▸ NPY1R P25929 4/20 0.57
▸ RAMP3 O60896 1/20 0.57
▸ CALCR P30988 1/20 0.57
▸ TFPI P10646 4/20 0.57
▸ CXCR4 P61073 1/20 0.56
▸ GLP1R P43220 3/20 0.56
▸ GCGR P47871 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31303098 0.92 NMUR2 (0.62) NMUR2NMUR1APLNRNPY2RNPY4R
SCHEMBL30842169 0.88 NMUR2 (0.65) NMUR2NMUR1APLNRTFPI
SCHEMBL29586781 0.88 OPRM1 (0.57) NMUR2NMUR1APLNRRAMP3CALCR
SCHEMBL30842159 0.88 NMUR2 (0.64) NMUR2NMUR1APLNRTFPICXCR4
SCHEMBL30432935 0.88 NMUR2 (0.61) NMUR2NMUR1NPY2RNPY4RNPY5R
SCHEMBL30495655 0.88 NMUR2 (0.64) NMUR2NMUR1NPY2RNPY4RNPY5R
SCHEMBL29697076 0.87 NMUR2 (0.62) NMUR2NMUR1RAMP3CALCRTFPI
SCHEMBL31183013 0.87 NPY2R (0.64) NPY2RNPY4RNPY5RNPY1RRAMP3
SCHEMBL29410232 0.86 KEAP1 (0.67) NMUR2NMUR1NPY2RNPY4RNPY5R
SCHEMBL31121841 0.86 NMUR2 (0.68) NMUR2NMUR1NPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642475-A2 ARTIFICIAL SECRETION PEPTIDES FOR HETEROLOGOUS PROTEIN PRODUCTION Tenza, Inc. (US) 2025-11-05 — — EP claimed
US-20250221968-A1 TREATMENTS AND METHODS FOR INCREASING DOPAMINE UNIV OXFORD INNOVATION LTD (GB) 2025-07-10 — — US claimed
EP-4493171-A1 NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST/BLOCKER FOR USE IN INCREASING DOPAMINE Zhang, Yanfeng C/o Oxford University Innovation Limited (GB) 2025-01-22 — — EP claimed
WO-2024145571-A2 ARTIFICIAL SECRETION PEPTIDES FOR HETEROLOGOUS PROTEIN PRODUCTION TENZA, INC. (US) 2024-07-04 — — WO claimed
WO-2023175357-A1 NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST/BLOCKER FOR USE IN INCREASING DOPAMINE OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-09-21 — — WO claimed
US-12631654-B2 Non-invasive assay for detecting and monitoring systemic inflammation ICHILOV TECH LTD. (IL) 2026-05-19 — — US disclosed
CN-117024411-B Isoquinoline as HPK1 inhibitor 豪夫迈·罗氏有限公司 2026-05-19 — — CN disclosed
WO-2026096690-A1 COMPOSITIONS AND METHODS TO TREAT NEURODEGENERATION AND COGNITIVE DECLINE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-07 — — WO disclosed
WO-2026095932-A1 COMPOSITIONS AND METHODS TO TREAT NEURODEGENERATION AND COGNITIVE DECLINE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-07 — — WO disclosed
EP-4642475-A2 ARTIFICIAL SECRETION PEPTIDES FOR HETEROLOGOUS PROTEIN PRODUCTION Tenza, Inc. (US) 2025-11-05 — — EP disclosed
US-20250327816-A1 BIOMARKERS FOR THE PREDICTION OF PRETERM BIRTH UNIVERSITé LAVAL (CA) 2025-10-23 — — US disclosed
EP-3732489-B1 NOVEL BIOMARKERS AND METHODS FOR DIAGNOSING AND EVALUATING TRAUMATIC BRAIN INJURY ABBOTT LAB (US) 2025-10-22 — — EP disclosed
CN-217033966-U Kit for combined detection of catastatin and NT-proBNP in sample 北京大学第三医院(北京大学第三临床医学院) 2022-07-22 — — CN disclosed
CN-217033966-U Kit for combined detection of catastatin and NT-proBNP in sample 北京大学第三医院(北京大学第三临床医学院) 2022-07-22 — — CN disclosed
CN-217033966-U Kit for combined detection of catastatin and NT-proBNP in sample 北京大学第三医院(北京大学第三临床医学院) 2022-07-22 — — CN disclosed
CN-217033965-U Kit for combined detection of catastatin, BNP and NT-proBNP in sample 北京大学第三医院(北京大学第三临床医学院) 2022-07-22 — — CN disclosed
US-20220211914-A1 HYALURONIC ACID HYDROGELS WITH PROLONGED ANTIMICROBIAL ACTIVITY SPARTHA MEDICAL (FR) 2022-07-07 — — US disclosed
US-20220213461-A1 ASX-SPECIFIC PROTEIN LIGASES AND USES THEREOF NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-07-07 — — US disclosed
EP-3966321-A1 ASX-SPECIFIC PROTEIN LIGASES AND USES THEREOF Nanyang Technological University (SG) 2022-03-16 — — EP disclosed
EP-3962543-A1 HYALURONIC ACID HYDROGELS WITH PROLONGED ANTIMICROBIAL ACTIVITY Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2022-03-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12631654-B2 Non-invasive assay for detecting and monitoring systemic inflammation CXCL10, MIF, CXCL8 NMUR2 348/4885NMUR1 781/4885APLNR 478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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