Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240107 | 0.97 | HTR6 (0.38) | ADRB3HTR6ALDH1A1L3MBTL1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL2948615 | 0.93 | SMN1; SMN2 (0.40) | ADRB3HTR6SMN1; SMN2MAPTADRB2 | |
| Trifluoroacetic Acid SCHEMBL28775802 | 0.91 | ADRB3 (0.39) | ADRB3HTR6ADRB2ADRB1 | |
| Trifluoroacetic Acid SCHEMBL2941086 | 0.91 | ADRB3 (0.39) | ADRB3HTR6ADRB2ADRB1 | |
| SCHEMBL13240065 | 0.89 | SMN1; SMN2 (0.42) | ADRB3HTR6SMN1; SMN2MAPTADRB2 | |
| Trifluoroacetic Acid SCHEMBL2949954 | 0.89 | ADRB3 (0.36) | ADRB3HTR6ALDH1A1SMN1; SMN2POLB | |
| Trifluoroacetic Acid SCHEMBL2943684 | 0.89 | ADRB3 (0.39) | ADRB3HTR6SMN1; SMN2POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL27739497 | 0.89 | ADRB3 (0.39) | ADRB3HTR6SMN1; SMN2POLBMAPT | |
| Trifluoroacetic Acid SCHEMBL2953642 | 0.89 | ADRB3 (0.37) | ADRB3HTR6POLBADRB2ADRB1 | |
| Trifluoroacetic Acid SCHEMBL27739597 | 0.89 | ADRB3 (0.37) | ADRB3HTR6POLBADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754756-B2 | Indol-containing beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-13 | — | — | US | disclosed |
| US-20070105906-A1 | Indol-containing beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105906-A1 | Indol-containing beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | ADRB1, ADRB3, ADRB2 | ADRB3 2/4885HTR6 172/4885ALDH1A1 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.