Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501799 | 0.93 | KLK7 (0.47) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL31058627 | 0.87 | PLG (0.32) | KLK7KLK5CA1CA2TDP1 | |
| SCHEMBL29501759 | 0.85 | ITGB3 (0.37) | KLK7KLK5ITGB3ITGA2B | |
| SCHEMBL22834294 | 0.85 | ITGB3 (0.37) | KLK7KLK5ITGB3ITGA2B | |
| SCHEMBL22834296 | 0.85 | ITGB3 (0.37) | KLK7KLK5ITGB3ITGA2B | |
| SCHEMBL30134454 | 0.85 | ITGB3 (0.42) | ITGB3SIRT2SIRT1SIRT3FOLH1 | |
| SCHEMBL12637855 | 0.83 | KLK7 (0.39) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL31058628 | 0.83 | ALDH1A1 (0.37) | KLK7KLK5ITGB3ITGA2BCA1 | |
| SCHEMBL31758414 | 0.82 | PTGER4 (0.41) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL29401366 | 0.82 | ITGB3 (0.44) | ITGB3SIRT2SIRT1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3989997-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS | Washington University (US) | 2022-05-04 | — | — | EP | disclosed |