Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29501775 | 0.93 | KLK7 (0.44) | KLK7KLK5MAPTITGB3ITGA2B | |
| SCHEMBL30134454 | 0.92 | ITGB3 (0.42) | ITGB3MMP2MMP9CPB1CPB2 | |
| SCHEMBL31058628 | 0.90 | ALDH1A1 (0.37) | KLK7KLK5ITGB3ITGA2BMMP9 | |
| SCHEMBL29398651 | 0.90 | ITGB3 (0.44) | ITGB3MMP2MMP9FOLH1 | |
| SCHEMBL29401366 | 0.90 | ITGB3 (0.44) | ITGB3MMP2MMP9FOLH1 | |
| SCHEMBL16893643 | 0.88 | ALDH1A1 (0.41) | KLK7KLK5ITGB3ITGA2BALDH1A1 | |
| SCHEMBL30918351 | 0.88 | ALDH1A1 (0.35) | KLK7KLK5ALDH1A1TSHR | |
| SCHEMBL20561238 | 0.88 | ALDH1A1 (0.39) | KLK7KLK5ITGB3ITGA2BALDH1A1 | |
| SCHEMBL29401007 | 0.88 | ALDH1A1 (0.39) | KLK7KLK5ITGB3ITGA2BALDH1A1 | |
| SCHEMBL15407157 | 0.88 | ALDH1A1 (0.39) | KLK7KLK5ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3989997-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER, VIRAL INFECTIONS, AND ALLERGIC CONDITIONS | Washington University (US) | 2022-05-04 | — | — | EP | disclosed |