SCHEMBL29501804

SCHEMBL29501804

COc1ccnc(C(=O)NC(C)C(=O)O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.47
EGLN1 Q9GZT9 4/20 0.46
BBOX1 O75936 2/20 0.46
FTO Q9C0B1 1/20 0.46
CTSA P10619 1/20 0.40
EGLN3 Q9H6Z9 1/20 0.39
SHMT2 P34897 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
GPR132 Q9UNW8 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2C Q14957 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17892017 1.00 KDM4C (0.47) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL20876090 1.00 KDM4C (0.47) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL21914754 1.00 KDM4C (0.47) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL30473365 0.89 MEN1 (0.41) CTSASMN1; SMN2TAS1R3TAS1R1ALDH1A1
SCHEMBL20892686 0.89 MEN1 (0.41) CTSASMN1; SMN2TAS1R3TAS1R1ALDH1A1
SCHEMBL26430243 0.89 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL20886342 0.89 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL26430148 0.89 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL20886341 0.88 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL19897488 0.88 KDM4C (0.40) KDM4CEGLN1BBOX1FTOCTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710429-B1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2023-04-05 EP disclosed
US-11291205-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291205-B2 Microbiocidal picolinamide derivatives CASP2, CASP1, MSR1 KDM4C 4224/4885EGLN1 1146/4885BBOX1 1049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.