SCHEMBL17892017

SCHEMBL17892017

COc1ccnc(C(=O)N[C@@H](C)C(=O)O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.47
EGLN1 Q9GZT9 4/20 0.46
BBOX1 O75936 2/20 0.46
FTO Q9C0B1 1/20 0.46
CTSA P10619 1/20 0.40
EGLN3 Q9H6Z9 1/20 0.39
SHMT2 P34897 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
GPR132 Q9UNW8 1/20 0.37
GRIN3B O60391 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2C Q14957 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20876090 1.00 KDM4C (0.47) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL21914754 1.00 KDM4C (0.47) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL29501804 1.00 KDM4C (0.47) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL30473365 0.89 MEN1 (0.41) CTSASMN1; SMN2TAS1R3TAS1R1ALDH1A1
SCHEMBL20892686 0.89 MEN1 (0.41) CTSASMN1; SMN2TAS1R3TAS1R1ALDH1A1
SCHEMBL26430243 0.89 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL20886342 0.89 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL26430148 0.89 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL20886341 0.88 CTSA (0.37) KDM4CEGLN1BBOX1FTOCTSA
SCHEMBL19897488 0.88 KDM4C (0.40) KDM4CEGLN1BBOX1FTOCTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024107910-A1 MIXTURES OF SUCCINATE DEHYDROGENASE INHIBITORS AND PICOLINAMIDES FMC CORPORATION (US) 2024-05-23 WO claimed
US-20230397607-A1 COMPOSITIONS COMPRISING MEFENTRIFLUCONAZOLE BASF Agro B.V. (NL) 2023-12-14 US claimed
CN-116209355-A Composition containing haloxyfop-methyl 巴斯夫农业公司 2023-06-02 CN claimed
EP-4110057-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2023-01-04 EP claimed
US-20220167615-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-06-02 US claimed
EP-3952652-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2022-02-16 EP claimed
WO-2021209360-A1 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2021-10-21 WO claimed
WO-2021148643-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2021-07-29 WO claimed
WO-2020208096-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-10-15 WO claimed
CN-122029155-A Heterocyclic compound and harmful arthropod control composition containing same 住友化学株式会社 2026-05-12 CN disclosed
CN-122029166-A Condensed cyclic compound and harmful arthropod control composition containing the same 住友化学株式会社 2026-05-12 CN disclosed
CN-115484825-B Phenyl compound and method for controlling plant disease 住友化学株式会社 2025-06-24 CN disclosed
CN-120019050-A Sulfonamide compound and harmful arthropod control composition containing same 住友化学株式会社 2025-05-16 CN disclosed
CN-119998283-A Sulfonamide compound and harmful arthropod control composition containing same 住友化学株式会社 2025-05-13 CN disclosed
US-20170369421-A1 PICOLINAMIDES WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC 2017-12-28 US disclosed
US-20170360038-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC 2017-12-21 US disclosed
EP-3240419-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY Dow Agrosciences LLC (US) 2017-11-08 EP disclosed
EP-3240420-A1 USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY Dow Agrosciences LLC (US) 2017-11-08 EP disclosed
WO-2016109303-A1 USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 2016-07-07 WO disclosed
WO-2016109302-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 2016-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170360038-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY PFAS, CASP2, CYP1A2 KDM4C 3182/4885EGLN1 905/4885BBOX1 1580/4885
US-20230397607-A1 COMPOSITIONS COMPRISING MEFENTRIFLUCONAZOLE CYP51A1, CYP3A43, CYP3A7 KDM4C 1257/4885EGLN1 500/4885BBOX1 2700/4885
US-20220167615-A1 FUNGICIDAL COMPOSITIONS CYP51A1, CYP4X1, CYP1B1 KDM4C 562/4885EGLN1 384/4885BBOX1 201/4885
US-20170369421-A1 PICOLINAMIDES WITH FUNGICIDAL ACTIVITY CYP51A1, CYP1A2, FKBP14 KDM4C 2876/4885EGLN1 974/4885BBOX1 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.