SCHEMBL29502637

SCHEMBL29502637

OC[C@H]1O[C@@H](n2cnc3c(Oc4ccccc4)ncnc32)C[C@@H]1O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 1/20 0.61
▸ SLC29A1 Q99808 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL657024 1.00 HIF1A (0.61) HIF1ASLC29A1
SCHEMBL13265483 1.00 HIF1A (0.61) HIF1ASLC29A1
SCHEMBL13265479 0.95 HIF1A (0.65) HIF1ASLC29A1
SCHEMBL13265485 0.86 DNPH1 (0.62) HIF1ASLC29A1
SCHEMBL5982949 0.84 HIF1A (0.71) HIF1A
SCHEMBL5982940 0.84 HIF1A (0.71) HIF1A
SCHEMBL13265431 0.84 HIF1A (0.71) HIF1A
SCHEMBL13265444 0.83 HIF1A (0.69) HIF1A
SCHEMBL13239681 0.82 HPGD (0.43) HIF1ASLC29A1
SCHEMBL15165603 0.82 HPGD (0.43) HIF1ASLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343990-B Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2025-05-30 — — CN disclosed
CN-112703256-B Method for determining polymer sequences 牛津纳米孔科技公开有限公司 2024-09-03 — — CN disclosed
CN-117343990-A Method and kit for determining target polynucleotide and probe set 牛津纳米孔科技公开有限公司 2024-01-05 — — CN disclosed
WO-2023147565-A2 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS Opentrons LabWorks Inc. (US) 2023-08-03 — — WO disclosed
US-20230046363-A1 METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-02-16 — — US disclosed
CN-115491373-A CRISPR/CAS related methods and compositions for treating herpes simplex virus 爱迪塔斯医药公司 2022-12-20 — — CN disclosed
CN-109312338-B CRISPR/CAS related methods and compositions for treating herpes simplex virus 爱迪塔斯医药公司 2022-09-27 — — CN disclosed
US-11390884-B2 Optimized CRISPR/cas9 systems and methods for gene editing in stem cells EDITAS MEDICINE, INC. (US) 2022-07-19 — — US disclosed
CN-107690480-B Evaluation of CAS9 molecule/guide RNA molecule complexes 爱迪塔斯医药公司 2022-03-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11390884-B2 Optimized CRISPR/cas9 systems and methods for gene editing in stem cells ZFX, DCLRE1B, APOBEC3C HIF1A 1394/4885SLC29A1 2238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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