SCHEMBL657024

SCHEMBL657024

OC[C@H]1O[C@@H](n2cnc3c(Oc4ccccc4)ncnc32)C[C@@H]1O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 1/20 0.61
▸ SLC29A1 Q99808 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13265483 1.00 HIF1A (0.61) HIF1ASLC29A1
SCHEMBL29502637 1.00 HIF1A (0.61) HIF1ASLC29A1
SCHEMBL13265479 0.95 HIF1A (0.65) HIF1ASLC29A1
SCHEMBL13265485 0.86 DNPH1 (0.62) HIF1ASLC29A1
SCHEMBL5982949 0.84 HIF1A (0.71) HIF1A
SCHEMBL5982940 0.84 HIF1A (0.71) HIF1A
SCHEMBL13265431 0.84 HIF1A (0.71) HIF1A
SCHEMBL13265444 0.83 HIF1A (0.69) HIF1A
SCHEMBL13239681 0.82 HPGD (0.43) HIF1ASLC29A1
SCHEMBL15165603 0.82 HPGD (0.43) HIF1ASLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713450-A1 ENGINEERED CONSTRUCTS WITH CASSETTE ARRANGEMENTS FOR INCREASED TRANSCRIPTION OF RNA PAYLOADS Shape Therapeutics Inc. (US) 2026-03-25 — — EP disclosed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 — — US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 — — US disclosed
US-12545912-B2 CRISPR/Cas-related methods and compositions for treating usher syndrome and retinitis pigmentosa EDITAS MEDICINE, INC. (US) 2026-02-10 — — US disclosed
EP-4677093-A2 MIRNA FOR CONTROLLING EXPRESSION OF IN VIVO DELIVERY CONSTRUCTS CREATE Medicines, Inc. (US) 2026-01-14 — — EP disclosed
EP-4652278-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER Aptah Bio, Inc. (US) 2025-11-26 — — EP disclosed
EP-4652279-A2 COMPOSITIONS FOR MODULATING KRAS EXPRESSION AND USES THEREOF Molecular Axiom, LLC (US) 2025-11-26 — — EP disclosed
EP-4652277-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES Aptah Bio, Inc. (US) 2025-11-26 — — EP disclosed
EP-4638752-A2 ENGINEERED GUIDE RNAS AND POLYNUCLEOTIDES Shape Therapeutics Inc. (US) 2025-10-29 — — EP disclosed
US-20250320491-A1 CRISPR-CPF1-RELATED METHODS, COMPOSITIONS AND COMPONENTS FOR CANCER IMMUNOTHERAPY EDITAS MEDICINE, INC. (US) 2025-10-16 — — US disclosed
US-9410189-B2 Methods of preventing non-specific reactions of nucleotide sequences CO-DIAGNOSTICS, INC. (US) 2016-08-09 — — US disclosed
US-20120045796-A1 NUCLEIC ACID HOTSTART TECHNOLOGY CO-DIAGNOSTICS, INC. 2012-02-23 — — US disclosed
US-20100317004-A1 PROBES Life Technologies Corporation (US) 2010-12-16 — — US disclosed
EP-2242761-A1 METHOD OF MYCOTOXIN DETECTION Neoventures Biotechnology Inc. (CA) 2010-10-27 — — EP disclosed
US-7608402-B2 DNA methylation specific signal amplification LI WEIWEI 2009-10-27 — — US disclosed
WO-2009086621-A1 METHOD OF MYCOTOXIN DETECTION NEOVENTURES BIOTECHNOLOGY INC. (CA) 2009-07-16 — — WO disclosed
EP-1585835-B1 Nucleic acid probes and method for detecting a target nucleic acid sequence comprising two or more cis-located nucleic acid regions DYNAL BIOTECH LTD (GB) 2007-04-18 — — EP disclosed
US-20060269916-A1 Probes DYNAL BIOTECH INC. 2006-11-30 — — US disclosed
EP-1585835-A2 NUCLEIC ACID PROBES AND METHOD FOR DETECTING A TARGET NUCLEIC ACID SEQUENCE COMPRISE TWO OR MORE CIS- LOCATED NUCLEIC ACID REGIONS Dynal Biotech Limited (GB) 2005-10-19 — — EP disclosed
WO-2004048611-A2 NUCLEIC ACID PROBES AND METHOD FOR DETECTING A TARGET NUCLEIC ACID SEQUENCE COMPRISE TWO OR MORE CIS- LOCATED NUCLEIC ACID REGIONS DYNAL BIOTECH LIMITED (GB) 2004-06-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM HIF1A 3888/4885SLC29A1 90/4885
US-12545912-B2 CRISPR/Cas-related methods and compositions for treating usher syndrome and retinitis pigmentosa UPF1, RPRD2, NR2E3 HIF1A 3930/4885SLC29A1 1126/4885
US-20250320491-A1 CRISPR-CPF1-RELATED METHODS, COMPOSITIONS AND COMPONENTS FOR CANCER IMMUNOTHERAPY TP53, DCAF1, RTF1 HIF1A 1072/4885SLC29A1 4738/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 HIF1A 1162/4885SLC29A1 813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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