Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241551 | 1.00 | KMT2A (0.69) | KMT2ANPC1RAB9AFKBP5MAPT | |
| SCHEMBL11595244 | 0.91 | KMT2A (0.70) | KMT2ANPC1RAB9AFKBP5MAPT | |
| SCHEMBL15846834 | 0.87 | NPC1 (0.66) | KMT2ANPC1RAB9AFKBP5MAPT | |
| SCHEMBL3530325 | 0.87 | KMT2A (0.69) | KMT2ANPC1RAB9AFKBP5MAPT | |
| SCHEMBL19070454 | 0.87 | MAPT (0.59) | KMT2ANPC1RAB9AFKBP5MAPT | |
| SCHEMBL4748653 | 0.86 | KCNK3 (0.69) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL4409156 | 0.85 | KCNK3 (0.65) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL28622654 | 0.85 | RAB9A (0.93) | KMT2ANPC1RAB9AFKBP5MAPT | |
| SCHEMBL31524185 | 0.84 | GAA (0.62) | KMT2ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11574601 | 0.84 | NPC1 (0.56) | KMT2ANPC1RAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430994-B | Compounds, compositions and methods for modulating CFTR | 蛋白质平衡治疗股份有限公司 | 2022-04-12 | — | — | CN | disclosed |