Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 10/20 | 0.69 |
| ▸ | KCNK9 | Q9NPC2 | 8/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22025458 | 0.88 | MEN1 (0.69) | KCNK3KCNK9KCNH2KMT2AMEN1 | |
| SCHEMBL15006333 | 0.86 | KCNK3 (0.76) | KCNK3KCNK9KCNH2KMT2AMEN1 | |
| SCHEMBL3241551 | 0.86 | KMT2A (0.69) | KCNK3KCNK9KMT2AMEN1NPC1 | |
| SCHEMBL29502995 | 0.86 | KMT2A (0.69) | KCNK3KCNK9KMT2AMEN1NPC1 | |
| SCHEMBL19070454 | 0.86 | MAPT (0.59) | KCNK3KCNK9KCNH2KMT2AMEN1 | |
| SCHEMBL3101556 | 0.86 | RAB9A (0.59) | KCNK3KCNK9KCNH2KMT2AMEN1 | |
| SCHEMBL12192807 | 0.86 | KCNK3 (0.64) | KCNK3KCNK9RXFP1NPC1RAB9A | |
| SCHEMBL12065272 | 0.85 | KMT2A (0.52) | KCNK3KCNK9KCNH2KMT2AMEN1 | |
| SCHEMBL5897054 | 0.83 | MAPK14 (0.65) | KCNK3RAB9ATP53KDM4EMAPT | |
| SCHEMBL15846834 | 0.83 | NPC1 (0.66) | KMT2AMEN1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794565-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2008124393-A1 | BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-10-16 | — | — | WO | disclosed |