Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
| ▸ | SQLE | Q14534 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3751818 | 0.82 | ALOX15 (0.56) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL3751814 | 0.82 | ALOX15 (0.56) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL12997108 | 0.82 | ALOX15 (0.56) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL28342394 | 0.79 | KMT2A (0.70) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL27437786 | 0.79 | KMT2A (0.70) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL19841923 | 0.78 | KMT2A (0.67) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL23802597 | 0.76 | KMT2A (1.00) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| Squalene SCHEMBL8819997 | 0.76 | KMT2A (1.00) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL8013144 | 0.76 | KMT2A (1.00) | KMT2AALOX15MAPTMEN1CYP3A4 | |
| SCHEMBL21639794 | 0.76 | KMT2A (1.00) | KMT2AALOX15MAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062725-A1 | METHOD FOR PURIFYING (-)-AMBROX | GIVAUDAN SA (CH) | 2026-03-05 | — | — | US | disclosed |
| US-20260043058-A1 | SHC ENZYMES AND ENZYME VARIANTS | GIVAUDAN SA (CH) | 2026-02-12 | — | — | US | disclosed |
| US-20250361536-A1 | SQUALENE HOPENE CYCLASE (SHC) VARIANTS | GIVAUDAN SA (CH) | 2025-11-27 | — | — | US | disclosed |
| US-12416027-B2 | Squalene hopene cyclase (SHC) variants | GIVAUDAN SA (CH) | 2025-09-16 | — | — | US | disclosed |
| EP-4613868-A2 | SQUALENE HOPENE CYCLASE DERIVATIVES AND USE THEREOF FOR PRODUCING AMBROX | International Flavors & Fragrances Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| US-12404531-B2 | Method for purifying (−)-Ambrox | GIVAUDAN SA (CH) | 2025-09-02 | — | — | US | disclosed |
| EP-4208546-B1 | SQUALENE HOPENE CYCLASE DERIVATIVES AND USE THEREOF FOR PRODUCING AMBROX | INT FLAVORS & FRAGRANCES INC (US) | 2025-05-21 | — | — | EP | disclosed |
| EP-4493685-A1 | SHC ENZYMES AND ENZYME VARIANTS | Givaudan SA (CH) | 2025-01-22 | — | — | EP | disclosed |
| CN-119137269-A | SHC enzyme and enzyme variants | 奇华顿股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20240368647-A1 | ENZYMES AND APPLICATIONS THEREOF | PROTEUS SA (FR) | 2024-11-07 | — | — | US | disclosed |
| US-20230220431-A1 | ENZYMES AND APPLICATIONS THEREOF | GIVAUDAN SA (CH) | 2023-07-13 | — | — | US | disclosed |
| EP-4208546-A2 | SQUALENE HOPENE CYCLASE DERIVATIVES AND USE THEREOF FOR PRODUCING AMBROX | International Flavors & Fragrances Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| US-20230212624-A1 | METHOD FOR PURIFYING (-)-AMBROX | GIVAUDAN SA (CH) | 2023-07-06 | — | — | US | disclosed |
| CN-116348602-A | Squalene-hopene cyclase derivatives and their use for the production of ambrox | 国际香料和香精公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20230021613-A1 | SQUALENE HOPENE CYCLASE (SHC) VARIANTS | GIVAUDAN SA (CH) | 2023-01-26 | — | — | US | disclosed |
| EP-4069836-A1 | SQUALENE HOPENE CYCLASE (SHC) VARIANTS | Givaudan SA (CH) | 2022-10-12 | — | — | EP | disclosed |
| US-11466299-B2 | Enzymes and applications thereof | GIVAUDAN S.A. (CH) | 2022-10-11 | — | — | US | disclosed |
| CN-115052982-A | Squalene agamene cyclase (SHC) variants | 奇华顿股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114438147-A | Enzyme and use thereof | 奇华顿股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| WO-2022051761-A2 | SQUALENE HOPENE CYCLASE DERIVATIVES AND USE THEREOF FOR PRODUCING AMBROX | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2022-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368647-A1 | ENZYMES AND APPLICATIONS THEREOF | HAO1, HLCS, HACL2 | KMT2A 3229/4885ALOX15 1237/4885MAPT 4855/4885 |
| US-20260043058-A1 | SHC ENZYMES AND ENZYME VARIANTS | SQLE, DHCR7, CYP51A1 | KMT2A 3526/4885ALOX15 231/4885MAPT 4866/4885 |
| US-20230220431-A1 | ENZYMES AND APPLICATIONS THEREOF | HAO1, HLCS, HACL2 | KMT2A 3229/4885ALOX15 1237/4885MAPT 4855/4885 |
| US-20260062725-A1 | METHOD FOR PURIFYING (-)-AMBROX | TAS2R7, TAS2R3, TAS2R13 | KMT2A 3026/4885ALOX15 1324/4885MAPT 3797/4885 |
| US-11466299-B2 | Enzymes and applications thereof | HAO1, HLCS, HACL2 | KMT2A 3229/4885ALOX15 1237/4885MAPT 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.