Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | USP5 | P45974 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | USP3 | Q9Y6I4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505212 | 0.87 | LMNA (0.51) | TP53LMNAUSP5HDAC6NPSR1 | |
| SCHEMBL29505176 | 0.81 | TP53 (0.44) | TP53LMNAPKMALDH1A1MEN1 | |
| SCHEMBL29505338 | 0.77 | EGLN1 (0.56) | LMNAMEN1KMT2A | |
| SCHEMBL5915276 | 0.76 | TP53 (0.74) | TP53LMNAUSP5HDAC6PKM | |
| SCHEMBL29505107 | 0.76 | MEN1 (0.58) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6949494 | 0.74 | TP53 (0.77) | TP53LMNAUSP5CNR1NPSR1 | |
| SCHEMBL29505198 | 0.74 | LMNA (0.56) | TP53LMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL29505193 | 0.74 | GRM5 (0.54) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5249802 | 0.72 | LMNA (0.71) | TP53LMNACNR1PKMALDH1A1 | |
| SCHEMBL29505112 | 0.72 | ROCK2 (0.46) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315794-A | 5-aliphatic heterocyclic group-3-hydroxypyridine-2-formyl glycine compound, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-04-12 | — | — | CN | disclosed |