Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | S100B | P04271 | 1/20 | 0.43 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1566908 | 0.83 | KMT2A (0.69) | KMT2AMAPTGFERRAB9AGRIN2D | |
| SCHEMBL2445867 | 0.83 | KMT2A (0.69) | KMT2AMAPTGFERRAB9AGRIN2D | |
| SCHEMBL1566907 | 0.83 | KMT2A (0.69) | KMT2AMAPTGFERRAB9AGRIN2D | |
| Anisaldehyde SCHEMBL2956046 | 0.79 | ALDH1A1 (0.66) | KMT2AMAPTRAB9AMEN1CYP1A2 | |
| SCHEMBL7311590 | 0.73 | MAPT (0.62) | KMT2AMAPTMEN1LMNAHPGD | |
| SCHEMBL2958835 | 0.72 | KDM4E (0.43) | KMT2AMAPTHPGDALDH1A1 | |
| SCHEMBL8068350 | 0.72 | TRPM8 (0.57) | RAB9ALMNAALDH1A1NPC1 | |
| P-Anisic Acid SCHEMBL6590201 | 0.71 | CA1 (0.67) | RAB9APOLBSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7447320 | 0.71 | NPC1 (0.49) | KMT2AMAPTRAB9APOLBSMN1; SMN2 | |
| P-Anisic Acid SCHEMBL6586036 | 0.70 | CA1 (0.65) | RAB9APOLBSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7750009-B2 | Substituted pteridines for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-06 | — | — | US | disclosed |
| US-20060116373-A1 | Substituted pteridines for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116373-A1 | Substituted pteridines for the treatment of inflammatory diseases | LTC4S, TLR5, LTB4R2 | KMT2A 2516/4885MAPT 2694/4885GFER 2602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.