SCHEMBL29508997

SCHEMBL29508997

CCCC[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.44
SLC28A2 O43868 1/20 0.44
SLC29A1 Q99808 1/20 0.44
SLC28A3 Q9HAS3 1/20 0.44
P2RY14 Q15391 2/20 0.37
P2RY2 P41231 2/20 0.34
P2RY4 P51582 1/20 0.34
P2RY1 P47900 2/20 0.34
P2RY6 Q15077 2/20 0.33
PYGB P11216 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2546576 0.97 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL17748428 0.96 SLC28A1 (0.42) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL6879975 0.93 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
Acetic Acid SCHEMBL27645915 0.93 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5567913 0.90 SLC28A1 (0.38) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL4064968 0.89 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL6389231 0.88 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL121731 0.88 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL29512365 0.88 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5616451 0.87 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229036-A9 NUCLEIC ACID MEDICINE EXPRESSING SPLICING VARIANT OF MYOSTATIN KNC LABORATORIES CO., LTD. (JP) 2024-07-11 US disclosed
US-20240132893-A1 NUCLEIC ACID MEDICINE EXPRESSING SPLICING VARIANT OF MYOSTATIN KNC LABORATORIES CO., LTD. (JP) 2024-04-25 US disclosed
US-11958878-B2 Therapeutic agent for glycogen storage disease type IA DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-04-16 US disclosed
EP-4299743-A1 NUCLEIC ACID MEDICINE EXPRESSING SPLICING VARIANT OF MYOSTATIN KNC Laboratories Co., Ltd. (JP) 2024-01-03 EP disclosed
US-20230272403-A1 ANTISENSE OLIGONUCLEOTIDE INDUCING EXON SKIPPING OF ANGIOTENSIN CONVERTING ENZYME 2 GENE KNC LABORATORIES CO., LTD. (JP) 2023-08-31 US disclosed
EP-4201484-A1 ANTISENSE NUCLEIC ACID INDUCING EXON SKIPPING OF ANGIOTENSIN CONVERTING ENZYME 2 GENE KNC Laboratories Co., Ltd. (JP) 2023-06-28 EP disclosed
CN-110636836-B P-ethoxy nucleic acids for STAT3 inhibition 拜奥-帕斯控股股份有限公司 2022-12-16 CN disclosed
EP-3146970-B1 NUCLEIC ACID DRUG FOR INDUCING SKIPPING OF VARIANT EXON OF CD44 GENE AND INCREASING EXPRESSION OF NORMAL TYPE CD44 MRNA KNC LABORATORIES CO LTD (JP) 2022-11-02 EP disclosed
US-20220220478-A1 NUCLEIC ACID DRUG SUPPRESSING PRODUCTION OF MYOSTATIN GENE MRNA KNC LABORATORIES CO., LTD. (JP) 2022-07-14 US disclosed
EP-3995153-A1 NUCLEIC ACID DRUG SUPPRESSING PRODUCTION OF MYOSTATIN GENE MRNA KNC Laboratories Co., Ltd. (JP) 2022-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958878-B2 Therapeutic agent for glycogen storage disease type IA G6PC1, GAA, GBA3 SLC28A1 97/4885SLC28A2 141/4885SLC29A1 623/4885
US-20220220478-A1 NUCLEIC ACID DRUG SUPPRESSING PRODUCTION OF MYOSTATIN GENE MRNA MYOF, MSTN, MTPN SLC28A1 69/4885SLC28A2 117/4885SLC29A1 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.