Toltrazuril

Toltrazuril

SCHEMBL29509205

Cc1cc(-n2c(=O)[nH]c(=O)n(C)c2=O)ccc1Oc1ccc(SC(F)(F)F)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 15/20 0.57
NTRK2 Q16620 15/20 0.57
IGF1R P08069 5/20 0.57
FGFR1 P11362 5/20 0.57
NTRK3 Q16288 11/20 0.46
BCAT2 O15382 4/20 0.38
BCAT1 P54687 4/20 0.38
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toltrazuril SCHEMBL21812043 1.00 NTRK1 (0.57) NTRK1NTRK2IGF1RFGFR1NTRK3
Toltrazuril SCHEMBL248912 1.00 NTRK1 (0.57) NTRK1NTRK2IGF1RFGFR1NTRK3
SCHEMBL13780159 0.92 NTRK1 (0.48) NTRK1NTRK2IGF1RFGFR1NTRK3
Toltrazuril SCHEMBL19436333 0.92 NTRK1 (0.49) NTRK1NTRK2IGF1RFGFR1NTRK3
SCHEMBL10975351 0.91 NTRK1 (0.52) NTRK1NTRK2IGF1RFGFR1NTRK3
SCHEMBL10525684 0.88 NTRK1 (0.58) NTRK1NTRK2IGF1RFGFR1NTRK3
SCHEMBL20328512 0.88 NTRK1 (0.76) NTRK1NTRK2IGF1RFGFR1NTRK3
SCHEMBL11478539 0.88 NTRK1 (0.45) NTRK1NTRK2IGF1RFGFR1NTRK3
SCHEMBL15783169 0.88 NTRK1 (0.55) NTRK1NTRK2IGF1RFGFR1NTRK3
SCHEMBL10525747 0.86 NTRK1 (0.51) NTRK1NTRK2IGF1RFGFR1NTRK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344836-B2 Treatment of parasitic infections of fish surfaces NEDERLANDS INSTITUUT VOOR ECOLOGIE (NIOO-KNAW) (NL) 2025-07-01 US disclosed
US-20240407371-A1 METHOD FOR THE KILLING, INACTIVATING, OR INHIBITING OF HARMFUL BLUE-GREEN ALGAE OR ALGAE CAPABLE OF CAUSING HARMFUL ALGAL BLOOM (HAB) SUNDEW APS (DK) 2024-12-12 US disclosed
EP-4415544-A1 METHOD FOR THE KILLING, INACTIVATING, OR INHIBITING OF HARMFUL BLUE-GREEN ALGAE OR ALGAE CAPABLE OF CAUSING HARMFUL ALGAL BLOOM (HAB) Sundew ApS (DK) 2024-08-21 EP disclosed
CN-116672360-B Composition of toltrazuril and iron glucoheptonate 重庆汉佩生物科技有限公司 2024-05-14 CN disclosed
CN-116672360-A Composition of toltrazuril and iron glucoheptonate 重庆汉佩生物科技有限公司 2023-09-01 CN disclosed
WO-2023061961-A1 METHOD FOR THE KILLING, INACTIVATING, OR INHIBITING OF HARMFUL BLUE-GREEN ALGAE OR ALGAE CAPABLE OF CAUSING HARMFUL ALGAL BLOOM (HAB) SUNDEW APS (DK) 2023-04-20 WO disclosed
US-20230107426-A1 Treatment of Parasitic Infections of Fish Surfaces NEDERLANDS INSTITUUT VOOR ECOLOGIE (NIOO-KNAW) (NL) 2023-04-06 US disclosed
US-20220087952-A1 ANTI-APICOMPLEXAN COMPOSITIONS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (IL) 2022-03-24 US disclosed