Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | CCR2 | P41597 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17712033 | 1.00 | ALOX5AP (0.35) | ALOX5APFEN1CCR2CA1CA2 | |
| SCHEMBL8176124 | 0.79 | CCR2 (0.38) | CCR2CA1CA2 | |
| SCHEMBL31001623 | 0.79 | CCR2 (0.38) | CCR2CA1CA2 | |
| SCHEMBL29509460 | 0.78 | RORC (0.38) | ALOX5APFEN1 | |
| SCHEMBL17711913 | 0.78 | RORC (0.38) | ALOX5APFEN1 | |
| SCHEMBL17711911 | 0.78 | RORC (0.38) | ALOX5APFEN1 | |
| SCHEMBL17711943 | 0.76 | RORC (0.40) | — | |
| SCHEMBL29509394 | 0.76 | RORC (0.40) | — | |
| SCHEMBL17711944 | 0.76 | RORC (0.40) | — | |
| SCHEMBL15916151 | 0.73 | CA1 (0.46) | ALOX5APFEN1CA1CA2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108064224-B | Amide-substituted thiazoles as modulators of Ror gamma t | 詹森药业有限公司 | 2022-03-29 | — | — | CN | disclosed |