SCHEMBL8176124

SCHEMBL8176124

CS(=O)(=O)c1ccc(Br)c(Cl)c1F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 5/20 0.38
EPAS1 Q99814 4/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
PTGS2 P35354 5/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
TSHR P16473 2/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31001623 1.00 CCR2 (0.38) CCR2EPAS1L3MBTL1PTGS2CA1
SCHEMBL4541463 0.84 TRPV4 (0.38) TSHRHTT
SCHEMBL2774283 0.84 CA2 (0.42) L3MBTL1CA1CA2LMNA
SCHEMBL3118107 0.83 CCR2 (0.38) CCR2EPAS1L3MBTL1CA1CA2
SCHEMBL6732039 0.81 L3MBTL1 (0.36) CCR2EPAS1L3MBTL1PTGS2CA1
SCHEMBL9448525 0.80 CCR2 (0.40) CCR2EPAS1L3MBTL1
SCHEMBL17712033 0.79 ALOX5AP (0.35) CCR2CA1CA2
SCHEMBL29509481 0.79 ALOX5AP (0.35) CCR2CA1CA2
SCHEMBL16564198 0.78 WDR5 (0.38) CCR2L3MBTL1CA1CA2HPGD
SCHEMBL16564207 0.77 WDR5 (0.37) CCR2L3MBTL1CA1CA2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112313209-B Herbicidal compounds 先正达农作物保护股份公司 2024-07-26 CN disclosed
US-11851411-B2 Herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2023-12-26 US disclosed
US-20210276962-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2021-09-09 US disclosed
CN-112313209-A Herbicidal compounds 先正达农作物保护股份公司 2021-02-02 CN disclosed
WO-2019243358-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2019-12-26 WO disclosed
US-6140271-A 1-ETHYL-4-(2-METHYL-3-(3-OXETANYLOXY)-4-METHYLSULFONYLBENZOYL) -5-HYDROXYPYRAZOLE, FOR EXAMPLE AND BENZOIC ACID CHEMICAL INTERMEDIATES; POSTEMERGENCE HERBICIDES DOW AGROSCIENCES LLC (US) 2000-10-31 US disclosed
US-5962690-A HERBICIDES DOW AGROSCIENCES LLC (US) 1999-10-05 US disclosed
EP-0918755-A1 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES Dow AgroSciences LLC (US) 1999-06-02 EP disclosed
US-5824802-A POSTEMERGENT HERBICIDE FOR CORN, WHEAT, BARLEY, RICE DOW AGROSCIENCES LLC (US) 1998-10-20 US disclosed
WO-1998042648-A1 2-BENZOYLCYCLOHEXANE-1,3-DIONE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 1998-10-01 WO disclosed
WO-1998042678-A1 1-ALKYL-4-BENZOYL-5-HYDROXYPYRAZOLE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 1998-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210276962-A1 HERBICIDAL COMPOUNDS DDT, CBR3, GLRX3 CCR2 1430/4885EPAS1 3963/4885L3MBTL1 828/4885
US-11851411-B2 Herbicidal compounds DDT, CBR3, GLRX3 CCR2 1430/4885EPAS1 3963/4885L3MBTL1 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.