Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 11/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 11/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17709790 | 1.00 | MEN1 (0.47) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL20919574 | 0.86 | MEN1 (0.46) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL17717292 | 0.82 | HSD11B1 (0.44) | — | |
| SCHEMBL309960 | 0.81 | NR1H2 (0.52) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL17711481 | 0.80 | AR (0.43) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL30320948 | 0.80 | AR (0.43) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL7101194 | 0.80 | SMN1; SMN2 (0.55) | MEN1ALOX15TSHRMAPK1KMT2A | |
| SCHEMBL3952493 | 0.79 | ESR1 (0.41) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5368422 | 0.79 | CYP1A2 (0.36) | MEN1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL29380184 | 0.79 | PDE2A (0.42) | TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108064224-B | Amide-substituted thiazoles as modulators of Ror gamma t | 詹森药业有限公司 | 2022-03-29 | — | — | CN | disclosed |