Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | CASP1 | P29466 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CASP7 | P55210 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009842 | 0.72 | CA2 (0.50) | CA9CA1CA2ALDH1A1NPC1 | |
| SCHEMBL18805433 | 0.72 | CA1 (0.50) | CA9CA1CA2ALDH1A1CASP1 | |
| SCHEMBL8056463 | 0.72 | CA1 (0.50) | CA9CA1CA2CA12ALDH1A1 | |
| SCHEMBL4934590 | 0.72 | CA12 (0.53) | CA9CA1CA2CA12ALDH1A1 | |
| SCHEMBL29641986 | 0.72 | CA12 (0.53) | CA9CA1CA2CA12ALDH1A1 | |
| SCHEMBL30827024 | 0.72 | CA12 (0.53) | CA9CA1CA2CA12ALDH1A1 | |
| SCHEMBL23029879 | 0.69 | CA1 (0.47) | CA9CA1CA2CA12ALDH1A1 | |
| SCHEMBL1503407 | 0.67 | CA12 (0.53) | CA9CA12ALDH1A1CASP1NPC1 | |
| SCHEMBL23030173 | 0.67 | CA1 (0.45) | CA9CA1CA2CA12SMN1; SMN2 | |
| SCHEMBL22058626 | 0.67 | CYP1A2 (0.47) | CA9CA1CA2CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11273154-B2 | Azole compounds as ubiquitin-specific protease USP7 inhibitors | PROGENRA, INC. (US) | 2022-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11273154-B2 | Azole compounds as ubiquitin-specific protease USP7 inhibitors | USP7, USP1, USP2 | CA9 729/4885CA1 773/4885CA2 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.