SCHEMBL4934590

SCHEMBL4934590

Nc1ccc2c(c1)S(=O)(=O)c1cc(N)ccc1-2

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.53
CA9 Q16790 3/20 0.53
GPR3 P46089 1/20 0.44
GAA P10253 3/20 0.43
MAPT P10636 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
HSD17B10 Q99714 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 2/20 0.43
RECQL P46063 1/20 0.43
NPC1 O15118 3/20 0.41
ALDH1A1 P00352 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
TSHR P16473 3/20 0.41
CYP3A4 P08684 2/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30827024 1.00 CA12 (0.53) CA12CA9GPR3GAAMAPT
SCHEMBL29641986 1.00 CA12 (0.53) CA12CA9GPR3GAAMAPT
SCHEMBL5185936 0.91 CA12 (0.47) CA12CA9GPR3GAAMAPT
SCHEMBL1369788 0.89 GPR3 (0.64) CA12CA9GPR3GAAMAPT
SCHEMBL1503407 0.89 CA12 (0.53) CA12CA9NPSR1CASP1CASP7
SCHEMBL17985424 0.88 ALDH1A1 (0.45) CA12CA9GPR3GAAMAPT
SCHEMBL14174131 0.86 GPR3 (0.59) CA12CA9GPR3GAAMAPT
SCHEMBL14174169 0.83 MAOA (0.47) CA12CA9GPR3GAAMAPT
SCHEMBL16900704 0.80 MEN1 (0.62) GPR3NPSR1L3MBTL1NPC1ALDH1A1
SCHEMBL12253556 0.80 GPR3 (0.44) CA12CA9GPR3GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6022307-A ANGIOGENESIS INHIBITOR AMERICAN CYANAMID COMPANY (US) 2000-02-08 US claimed
US-5360840-A MIXTURE OF A POLYEPOXIDE AND A CRYSTALLINE AROMATIC DIAMINE CURING AGENT HERCULES INCORPORATED (US) 1994-11-01 US claimed
EP-0604909-A2 Epoxy resin compositions with improved storage stability HERCULES INCORPORATED (US) 1994-07-06 EP claimed
JP-7002974-A None JP disclosed
CN-117772149-A PUF/COF composite material, preparation method and application thereof 山东威高血液净化制品股份有限公司 2024-03-29 CN disclosed
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer JNC CORPORATION (JP) 2021-04-06 US disclosed
CN-112533866-A Method for purifying nitrous oxide 昭和电工株式会社 2021-03-19 CN disclosed
US-20190127643-A1 LIQUID CRYSTAL ALIGNING AGENT FOR PHOTOALIGNMENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE USING IT, AND DIAMINE AND POLYMER JNC CORPORATION (JP) 2019-05-02 US disclosed
EP-3173401-A1 PROCESS FOR THE SYNTHESIS OF ARYLDIAZONIUM SALTS USING NITROGEN OXIDES IN OXYGEN-CONTAINING GAS STREAMS, ESPECIALLY FROM INDUSTRIAL WASTE GASES Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2017-05-31 EP disclosed
US-8734917-B2 Liquid crystal display device JAPAN DISPLAY INC. (JP) 2014-05-27 US disclosed
US-8734568-B2 Asymmetric hollow fiber gas separation membrane UBE INDUSTRIES, LTD. (JP) 2014-05-27 US disclosed
EP-0604909-A2 Epoxy resin compositions with improved storage stability HERCULES INCORPORATED (US) 1994-07-06 EP disclosed
EP-0604909-A2 Epoxy resin compositions with improved storage stability HERCULES INCORPORATED (US) 1994-07-06 EP disclosed
US-5292963-A Continuous, polyimide separating membrane UBE INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
US-4997462-A Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1991-03-05 US disclosed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP disclosed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US disclosed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP disclosed
US-4314015-A Electrophotographic sensitive materials containing disazo compounds RICOH CO., LTD. (JP) 1982-02-02 US disclosed
US-4299896-A Electrophotographic sensitive materials containing a disazo pigment RICOH CO., LTD. (JP) 1981-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer DDT, DCLRE1A, DVL1 CA12 2226/4885CA9 2201/4885GPR3 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.