SCHEMBL2951091

SCHEMBL2951091

[C]1c2ccccc2-c2cc3ccccc3cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 5/20 0.43
HPGD P15428 3/20 0.43
CASP1 P29466 3/20 0.43
HIF1A Q16665 3/20 0.43
TSHR P16473 3/20 0.43
MAPK1 P28482 3/20 0.43
TP53 P04637 2/20 0.43
CASP7 P55210 2/20 0.43
HBB P68871 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
ATM Q13315 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
NQO2 P16083 1/20 0.31
CYP2A6 P11509 5/20 0.30
ALOX12 P18054 1/20 0.30
GSTP1 P09211 1/20 0.30
CYP1A2 P05177 2/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL102781 0.80 MEN1 (0.37) ALDH1A1HSD17B10TSHRMAPK1TP53
SCHEMBL9039265 0.68 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDCASP1HIF1A
SCHEMBL9042905 0.68 ALDH1A1 (0.67) ALDH1A1HSD17B10HPGDCASP1HIF1A
SCHEMBL1979202 0.68 ALDH1A1 (0.67) ALDH1A1HSD17B10HPGDCASP1HIF1A
SCHEMBL5917389 0.68 ALDH1A1 (0.67) ALDH1A1HSD17B10HPGDCASP1HIF1A
SCHEMBL1154675 0.68 ALDH1A1 (0.67) ALDH1A1HSD17B10HPGDCASP1HIF1A
SCHEMBL28763536 0.68 ALDH1A1 (0.67) ALDH1A1HSD17B10HPGDCASP1HIF1A
SCHEMBL1811522 0.68 ALDH1A1 (0.67) ALDH1A1HSD17B10HPGDCASP1HIF1A
SCHEMBL8086154 0.67 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDTSHRMAPK1
SCHEMBL577831 0.65 CDC25B (0.58) ALDH1A1HPGDCASP1HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP claimed
CN-118043298-A (Hetero) aryl-substituted bisphenol compound and thermoplastic resin 罗伊特化学仪器制造公司 2024-05-14 CN claimed
CN-117940399-A Heteroaryl or aryl substituted bisphenol compounds and thermoplastic resins 三菱瓦斯化学株式会社 2024-04-26 CN claimed
WO-2023038156-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-16 WO claimed
EP-1805278-B1 PHOTOCHROMIC H-ANNELLATED BENZO(F)CHROME-DERIVATIVES RODENSTOCK GMBH (DE) 2010-01-06 EP claimed
US-7544315-B2 Photochromic h-annellated benzo[f]chromene compounds RODENSTOCK GMBH (DE) 2009-06-09 US claimed
US-20070246692-A1 For example, 2-(4-methoxyphenyl)-2-phenyl-2H-benzofurano[1,2-h]benzo[f]chromene; use in photochromic synthetic resin articles, particularly ophthalmic lenses RODENSTOCK GMBH (DE) 2007-10-25 US claimed
CN-118251380-A Spiro- (indan-fluorene) compounds and their use in organic electronic devices 多蒂肯独家合成控股公司 2024-06-25 CN disclosed
CN-118043298-A (Hetero) aryl-substituted bisphenol compound and thermoplastic resin 罗伊特化学仪器制造公司 2024-05-14 CN disclosed
CN-117940399-A Heteroaryl or aryl substituted bisphenol compounds and thermoplastic resins 三菱瓦斯化学株式会社 2024-04-26 CN disclosed
WO-2023208837-A1 OLIGOMERIC BINAPHTHYL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-11-02 WO disclosed
EP-3621946-B1 INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-09-06 EP disclosed
WO-2023078824-A1 SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-05-11 WO disclosed
US-4818443-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1989-04-04 US disclosed
US-4814502-A ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS BURROUGHS WELLCOME CO. (US) 1989-03-21 US disclosed
US-4810823-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1989-03-07 US disclosed
US-4808753-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1989-02-28 US disclosed
US-4791233-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1988-12-13 US disclosed
US-4791232-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1988-12-13 US disclosed
US-4791231-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1988-12-13 US disclosed