SCHEMBL29511037

SCHEMBL29511037

C[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 6/20 0.58
▸ OPRM1 P35372 2/20 0.55
▸ OPRD1 P41143 2/20 0.55
▸ IL23R Q5VWK5 1/20 0.53
▸ ACE P12821 1/20 0.51
▸ GHSR Q92847 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511018 1.00 KISS1R (0.58) KISS1ROPRM1OPRD1IL23RACE
SCHEMBL29476441 0.96 KISS1R (0.55) KISS1ROPRM1OPRD1IL23RACE
SCHEMBL29476439 0.96 KISS1R (0.55) KISS1ROPRM1OPRD1IL23RACE
SCHEMBL30264819 0.96 KISS1R (0.55) KISS1RIL23RACEGHSR
SCHEMBL30264955 0.96 KISS1R (0.55) KISS1RIL23RACEGHSR
SCHEMBL30264867 0.96 KISS1R (0.55) KISS1RIL23RACEGHSR
SCHEMBL30264784 0.96 KISS1R (0.55) KISS1RIL23RACEGHSR
SCHEMBL30786983 0.96 KISS1R (0.53) KISS1RACE
SCHEMBL31184496 0.96 KISS1R (0.53) KISS1RACE
SCHEMBL29476104 0.96 KISS1R (0.53) KISS1RACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 — — US disclosed
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R KISS1R 417/4885OPRM1 25/4885OPRD1 19/4885
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R KISS1R 155/4885OPRM1 216/4885OPRD1 359/4885
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R KISS1R 232/4885OPRM1 115/4885OPRD1 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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