SCHEMBL29511125

SCHEMBL29511125

N=C(N)NCCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCCC(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PRKACB P22694 1/20 0.57
▸ NPBWR1 P48145 2/20 0.54
▸ NMBR P28336 2/20 0.51
▸ GHSR Q92847 3/20 0.50
▸ BMP1 P13497 1/20 0.50
▸ C5AR1 P21730 1/20 0.49
▸ CXCR4 P61073 1/20 0.49
▸ NPY2R P49146 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29511199 0.94 NPBWR1 (0.57) PRKACBNPBWR1GHSR
SCHEMBL30866237 0.93 NPBWR1 (0.55) PRKACBNPBWR1NMBRGHSRC5AR1
SCHEMBL29641046 0.93 GHSR (0.56) PRKACBNMBRGHSRNPY2R
SCHEMBL30990571 0.93 GHSR (0.56) PRKACBNMBRGHSRNPY2R
SCHEMBL29511112 0.93 GHSR (0.56) PRKACBNMBRGHSRNPY2R
SCHEMBL29790169 0.92 GHSR (0.56) PRKACBNPBWR1NMBRGHSRNPY2R
SCHEMBL29484173 0.92 GHSR (0.56) PRKACBNPBWR1NMBRGHSRNPY2R
SCHEMBL29609768 0.92 GHSR (0.56) PRKACBNPBWR1NMBRGHSRNPY2R
SCHEMBL31593359 0.92 GHSR (0.56) PRKACBNPBWR1NMBRGHSRNPY2R
SCHEMBL29790108 0.92 GHSR (0.56) PRKACBNPBWR1NMBRGHSRNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
CN-119119190-A Melanocortin receptor ligands 益普生制药股份有限公司 2024-12-13 — — CN disclosed
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY IPSEN PHARMA SAS (FR) 2022-10-27 — — US disclosed
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R PRKACB 1262/4885NPBWR1 29/4885NMBR 204/4885
US-20220339239-A1 USE OF MELANOCORTINS TO TREAT INSULIN SENSITIVITY MC4R, MC1R, MC3R PRKACB 1401/4885NPBWR1 45/4885NMBR 138/4885
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R PRKACB 2607/4885NPBWR1 51/4885NMBR 92/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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