Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340709 | 0.82 | MEN1 (0.38) | GPR119USP2SMN1; SMN2NR1H2KDM4E | |
| SCHEMBL120243 | 0.80 | USP2 (0.50) | GPR119USP2SMN1; SMN2NR1H2KDM4E | |
| SCHEMBL27006656 | 0.74 | USP2 (0.46) | GPR119USP2SMN1; SMN2NR1H2KDM4E | |
| SCHEMBL995131 | 0.73 | USP2 (0.52) | GPR119USP2SMN1; SMN2NR1H2KDM4E | |
| SCHEMBL14800964 | 0.73 | USP2 (0.52) | USP2SMN1; SMN2NR1H2KDM4EMAPT | |
| SCHEMBL20765932 | 0.73 | USP2 (0.47) | GPR119USP2SMN1; SMN2NR1H2KDM4E | |
| SCHEMBL23466965 | 0.72 | RORC (0.41) | GPR119NR1H2 | |
| Hydrochloric Acid SCHEMBL26689433 | 0.72 | USP2 (0.50) | GPR119USP2SMN1; SMN2NR1H2KDM4E | |
| SCHEMBL29070006 | 0.71 | USP2 (0.44) | GPR119USP2SMN1; SMN2NR1H2KDM4E | |
| SCHEMBL19852271 | 0.70 | NR1H2 (0.46) | USP2SMN1; SMN2NR1H2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114437096-A | Spiro-heterocyclic compound, and preparation method and application thereof | 上海医药集团股份有限公司 | 2022-05-06 | — | — | CN | disclosed |