Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276741 | 1.00 | MMP12 (0.51) | MMP12CYP11B1CYP11B2PARP1KIF11 | |
| SCHEMBL277585 | 0.86 | MMP12 (0.65) | MMP12PARP1CA9ALDH1A1MAPT | |
| SCHEMBL30343101 | 0.86 | MMP12 (0.65) | MMP12PARP1CA9ALDH1A1MAPT | |
| SCHEMBL6297092 | 0.83 | CYP11B1 (0.64) | MMP12CYP11B1CYP11B2KIF11PDE3B | |
| SCHEMBL6302322 | 0.83 | ALDH1A1 (0.51) | MMP12CYP11B1CYP11B2PARP1KIF11 | |
| SCHEMBL6297460 | 0.83 | CYP11B1 (0.44) | MMP12CYP11B1CYP11B2PARP1KIF11 | |
| SCHEMBL28575263 | 0.83 | CA9 (0.51) | MMP12CYP11B1CYP11B2KIF11PDE3B | |
| SCHEMBL6295828 | 0.80 | CYP11B1 (0.44) | MMP12CYP11B1CYP11B2PARP1KIF11 | |
| SCHEMBL6295568 | 0.80 | ATM (0.50) | MMP12CYP11B1CYP11B2KIF11PDE3B | |
| SCHEMBL9437792 | 0.79 | DRD4 (0.53) | MMP12CYP11B1CYP11B2PARP1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-117924247-A | Triazole derivative with liver cancer cell activity inhibiting function, and preparation method and application thereof | 河南科技大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-110248937-B | 4, 5-Cyclic 1,2, 4-triazolones | 拜耳股份有限公司 | 2022-03-29 | — | — | CN | disclosed |