Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333071 | 1.00 | NCF1 (0.39) | NCF1MBOAT4ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23552527 | 0.77 | ALDH1A1 (0.37) | MBOAT4ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7886312 | 0.77 | MAPK8 (0.47) | ALDH1A1CYP1A2GRM4NPC1MAPT | |
| SCHEMBL23525752 | 0.77 | CCR4 (0.37) | — | |
| SCHEMBL23535480 | 0.77 | NPC1 (0.44) | ALDH1A1GRM4NPC1MAPT | |
| SCHEMBL30791387 | 0.77 | CCR4 (0.37) | — | |
| SCHEMBL6679844 | 0.76 | NCF1 (0.39) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6782662 | 0.76 | NCF1 (0.39) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7916840 | 0.76 | ALDH1A1 (0.42) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23552720 | 0.75 | SYK (0.41) | MBOAT4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076973-A1 | 7-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |