Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514172 | 0.91 | CSNK1A1 (0.39) | PGRCSNK1DCSNK1A1CSNK1ETNIK | |
| SCHEMBL30605084 | 0.82 | CSNK1D (0.48) | CSNK1DCSNK1A1CSNK1ETNIKHTR1A | |
| SCHEMBL30405671 | 0.77 | CYP2A6 (0.41) | ALDH1A1 | |
| SCHEMBL29514418 | 0.74 | CSNK1D (0.50) | CSNK1DCSNK1A1CSNK1ETNIKHTR1A | |
| SCHEMBL2523630 | 0.74 | TSHR (0.47) | CSNK1DKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL30605078 | 0.73 | KMT2A (0.35) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL30405663 | 0.73 | KMT2A (0.35) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL30605065 | 0.72 | LMNA (0.34) | CSNK1DKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL20939182 | 0.72 | KDM4E (0.33) | KMT2AMEN1TSHRKDM4EALDH1A1 | |
| SCHEMBL25227540 | 0.71 | TSHR (0.43) | KMT2AMEN1LMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214214-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |