Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 4/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.46 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514207 | 0.80 | CSNK1D (0.42) | CSNK1DCSNK1A1CSNK1ETNIKMAPK14 | |
| SCHEMBL29514172 | 0.73 | CSNK1A1 (0.39) | CSNK1DCSNK1A1CSNK1ETNIKHTR1A | |
| SCHEMBL29513353 | 0.73 | CSNK1D (0.56) | CSNK1DCSNK1A1CSNK1ETNIKMAPK14 | |
| SCHEMBL29514039 | 0.72 | CSNK1D (0.61) | CSNK1DCSNK1A1CSNK1ETNIKMAPK14 | |
| SCHEMBL30404081 | 0.71 | CSNK1D (0.66) | CSNK1DCSNK1A1CSNK1ETNIKMAPK14 | |
| SCHEMBL29514348 | 0.68 | MAPK14 (0.32) | CSNK1DMAPK14THRB | |
| SCHEMBL2522830 | 0.66 | THRB (0.53) | CSNK1DCSNK1EMAPK14THRB | |
| SCHEMBL29514170 | 0.66 | TGFBR1 (0.37) | MAPK14THRB | |
| SCHEMBL2527330 | 0.66 | HTR3A (0.36) | MAPK14HTR3AUGCG | |
| SCHEMBL2522571 | 0.65 | THRB (0.49) | CSNK1DCSNK1EMAPK14THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214214-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |