Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 4/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3261075 | 0.92 | PRMT5 (0.53) | RIPK1GPR119PRMT5WDR77ALDH1A1 | |
| SCHEMBL27504373 | 0.85 | RIPK1 (0.66) | RIPK1GPR119NR1H2NR1H3 | |
| SCHEMBL27703992 | 0.84 | GPR119 (0.53) | RIPK1GPR119PRMT5WDR77ALDH1A1 | |
| SCHEMBL30675171 | 0.84 | GPR119 (0.53) | RIPK1GPR119PRMT5WDR77ALDH1A1 | |
| SCHEMBL2148828 | 0.83 | RIPK1 (0.48) | RIPK1NR1H2NR1H3 | |
| SCHEMBL14880733 | 0.83 | NR1H2 (0.54) | RIPK1NR1H2NR1H3 | |
| SCHEMBL26115692 | 0.83 | PARP1 (0.43) | RIPK1GPR119PRMT5WDR77USP30 | |
| SCHEMBL29665905 | 0.83 | RIPK1 (0.40) | RIPK1GPR119PRMT5WDR77USP30 | |
| SCHEMBL38661096 | 0.82 | NR1H2 (0.47) | RIPK1GPR119USP30NR1H2NR1H3 | |
| SCHEMBL29514535 | 0.81 | PARP1 (0.39) | RIPK1GPR119PRMT5WDR77USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003667-B | TYK-2 inhibitors | 百济神州有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-114181205-A | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |