Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23778552 | 0.82 | HIF1A (0.44) | LMNANPSR1HIF1AHSD11B1P2RY1 | |
| SCHEMBL9051092 | 0.80 | HDAC4 (0.39) | HDAC4LMNAHSD11B1ALDH1A1KDM4E | |
| SCHEMBL31292311 | 0.80 | LMNA (0.51) | HDAC4LMNANPSR1HIF1AHSD11B1 | |
| SCHEMBL9052687 | 0.79 | HDAC4 (0.38) | HDAC4LMNAHSD11B1ALDH1A1KDM4E | |
| SCHEMBL26451965 | 0.76 | HSD17B10 (0.39) | HDAC4LMNAHIF1AHSD11B1ITGA4 | |
| SCHEMBL31382142 | 0.76 | OPRM1 (0.51) | LMNANPSR1HIF1AHSD11B1P2RY1 | |
| SCHEMBL28891928 | 0.74 | EGFR (0.41) | — | |
| SCHEMBL5376177 | 0.73 | HDAC4 (0.62) | HDAC4HSD11B1MEN1KMT2AKCNA3 | |
| Water SCHEMBL27993946 | 0.69 | HSD11B1 (0.40) | HSD11B1P2RY1ALDH1A1MEN1KMT2A | |
| SCHEMBL31382726 | 0.68 | TSHR (0.51) | HIF1AHSD11B1ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181205-A | Pyrazolopyridine compound or salt thereof, and preparation method and application thereof | 上海辉启生物医药科技有限公司 | 2022-03-15 | — | — | CN | disclosed |