Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 5/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25695039 | 1.00 | CCND1 (0.38) | CCND1CDK4CDK6 | |
| SCHEMBL24322143 | 0.85 | CCND1 (0.37) | CCND1CDK4CDK6 | |
| SCHEMBL24322338 | 0.77 | CCND1 (0.59) | CCND1CDK4CDK6 | |
| SCHEMBL29514841 | 0.71 | CCND1 (0.61) | CCND1CDK4CDK6 | |
| SCHEMBL24676493 | 0.68 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL29755049 | 0.68 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL394534 | 0.65 | ABL1 (0.34) | — | |
| SCHEMBL25695270 | 0.65 | CCND1 (0.41) | CCND1CDK4CDK6 | |
| SCHEMBL24054302 | 0.65 | ADORA2A (0.37) | — | |
| SCHEMBL4075180 | 0.63 | DCK (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214213-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | Prelude Therapeutics, Incorporated (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022061273-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2022-03-24 | — | — | WO | disclosed |