SCHEMBL29517104

SCHEMBL29517104

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nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 10/20 0.55
▸ MME P08473 9/20 0.55
▸ CPA1 P15085 2/20 0.55
▸ ACE2 Q9BYF1 2/20 0.55
▸ FOLH1 Q04609 1/20 0.53
▸ NAALAD2 Q9Y3Q0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31514357 0.92 FOLH1 (0.58) ACEMMECPA1ACE2FOLH1
SCHEMBL27852467 0.90 MME (0.53) ACEMMECPA1ACE2
SCHEMBL27852469 0.90 MME (0.53) ACEMMECPA1ACE2
SCHEMBL29839261 0.89 BACE1 (0.47) ACEMMECPA1ACE2FOLH1
SCHEMBL31257978 0.88 OPRD1 (0.57) ACEMME
SCHEMBL30974549 0.86 ACE (0.56) ACEMMECPA1ACE2FOLH1
SCHEMBL29349965 0.86 ACE (0.58) ACEMMECPA1ACE2FOLH1
SCHEMBL29527180 0.85 OPRD1 (0.58) ACEMMECPA1ACE2FOLH1
SCHEMBL30123357 0.85 ACE (0.55) ACEMMECPA1ACE2FOLH1
SCHEMBL31415936 0.85 OPRM1 (0.51) ACEMMECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024571-B2 Anti-erythropoietin receptor peptide EPO-MED INC. (JP) 2024-07-02 — — US disclosed
US-20230310539-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST EPO-MED INC. (JP) 2023-10-05 — — US disclosed
EP-4190345-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST Epo-Med Inc. (JP) 2023-06-07 — — EP disclosed
CN-116234541-A Treatment of diseases by EpoR antagonists EPO医药株式会社 2023-06-06 — — CN disclosed
WO-2022025204-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST エポメッド株式会社 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024571-B2 Anti-erythropoietin receptor peptide EPOR, PRLHR, AVPR1A ACE 3284/4885MME 568/4885CPA1 261/4885
US-20230310539-A1 TREATMENT OF DISEASE WITH EPOR ANTAGONIST EPOR, PROKR1, HBZ ACE 828/4885MME 185/4885CPA1 348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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