Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27752058 | 0.86 | RAB9A (0.67) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL12204615 | 0.78 | MEN1 (0.62) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL1224685 | 0.75 | LMNA (0.45) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL1224684 | 0.75 | LMNA (0.45) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL27752021 | 0.74 | RAB9A (0.67) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL1225513 | 0.72 | SMN1; SMN2 (0.45) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL1225516 | 0.72 | SMN1; SMN2 (0.45) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL18985299 | 0.72 | RAB9A (0.74) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL18985301 | 0.72 | RAB9A (0.74) | HTTLMNARAB9AMEN1KMT2A | |
| SCHEMBL3040771 | 0.71 | RAB9A (0.69) | HTTLMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022071777-A1 | COMPOSITION AND METHOD FOR PREVENTION OR TREATMENT OF RESPIRATORY DISEASE | 연세대학교 산학협력단 | 2022-04-07 | — | — | WO | disclosed |