Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605456 | 1.00 | ECE2 (0.48) | ECE2LMNAMAPK1HTTHSD11B1 | |
| SCHEMBL29518321 | 0.91 | PLD2 (0.45) | LMNAMAPK1HTTHSD11B1CHRM1 | |
| SCHEMBL22605644 | 0.91 | PLD2 (0.45) | LMNAMAPK1HTTHSD11B1CHRM1 | |
| SCHEMBL24368248 | 0.90 | LMNA (0.43) | ECE2LMNAMAPK1HTTHSD11B1 | |
| SCHEMBL29518269 | 0.89 | LMNA (0.42) | LMNAMAPK1HTTHSD11B1CHRM1 | |
| SCHEMBL24368352 | 0.89 | LMNA (0.42) | LMNAMAPK1HTTHSD11B1CHRM1 | |
| SCHEMBL22588684 | 0.88 | PLD2 (0.43) | ECE2LMNAMAPK1HTTHSD11B1 | |
| SCHEMBL31285924 | 0.88 | PLD2 (0.43) | ECE2LMNAMAPK1HTTHSD11B1 | |
| SCHEMBL24368260 | 0.88 | HSD11B1 (0.43) | LMNAMAPK1HTTHSD11B1CHRM1 | |
| SCHEMBL24368272 | 0.87 | LMNA (0.41) | LMNAMAPK1HTTHSD11B1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-116457347-A | Compound containing condensed rings, application thereof and composition containing compound | 健艾仕生物医药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114478482-A | Compound containing condensed ring, application thereof and composition containing compound | 健艾仕生物医药有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2022083731-A1 | FUSED RING-CONTAINING COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2022-04-28 | — | — | WO | disclosed |