Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22874230 | 0.78 | LIMK1 (0.54) | LIMK1CDK5CDK5R1KRASEGFR | |
| SCHEMBL13209223 | 0.75 | LIMK1 (0.51) | LIMK1CDK5CDK5R1KRASEGFR | |
| SCHEMBL16693325 | 0.75 | LIMK1 (0.51) | LIMK1CDK5CDK5R1KRASEGFR | |
| SCHEMBL19937109 | 0.75 | LIMK1 (0.51) | LIMK1CDK5CDK5R1KRASEGFR | |
| SCHEMBL16685432 | 0.75 | LIMK1 (0.51) | LIMK1CDK5CDK5R1KRASEGFR | |
| SCHEMBL29519419 | 0.75 | LIMK1 (0.51) | LIMK1CDK5CDK5R1KRASEGFR | |
| SCHEMBL16283936 | 0.75 | LIMK1 (0.47) | LIMK1CDK5CDK5R1KRASEGFR | |
| SCHEMBL30179985 | 0.73 | CDK1 (0.44) | LIMK1KRASMIFGABRA1MEN1 | |
| SCHEMBL15374732 | 0.73 | GPR3 (0.46) | LIMK1CDK5CDK5R1KRASMIF | |
| SCHEMBL24589835 | 0.72 | LIMK1 (0.49) | LIMK1CDK5CDK5R1KRASEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014324-A2 | DIAZEPINONES AS ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-02-21 | — | — | WO | claimed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |